Results 341 to 350 of about 15,304,481 (401)
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Tumor‐initiating cells and tumor vascularization
Pediatric Blood & Cancer, 2010AbstractTumor‐initiating cells (TICs) with stem‐like cell properties initiate and sustain progressive growth, resulting in a heterogeneous tumor mass. The survival and growth of tumors rely on the development of a vasculature to provide nutrients and oxygen. Crosstalk between TICs and vascularization may be one of the central players in the initiation,
Li-Zhi, Zhang +5 more
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Tumor heterogeneity and circulating tumor cells
Cancer Letters, 2016In patients with cancer, individualized treatment strategies are generally guided by an analysis of molecular biomarkers. However, genetic instability allows tumor cells to lose monoclonality and acquire genetic heterogeneity, an important characteristic of tumors, during disease progression.
Chufeng Zhang +4 more
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Ultrastructural Pathology, 1991
A case of islet cell tumor occurring in a patient with the multiple endocrine neoplasia type I syndrome is reported. Immunostaining for insulin was strongly positive in the tumor cells. Numerous dense-core granules of endocrine caliber were identified ultrastructurally.
B, Fitzpatrick, N G, Ordoñez, B, Mackay
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A case of islet cell tumor occurring in a patient with the multiple endocrine neoplasia type I syndrome is reported. Immunostaining for insulin was strongly positive in the tumor cells. Numerous dense-core granules of endocrine caliber were identified ultrastructurally.
B, Fitzpatrick, N G, Ordoñez, B, Mackay
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Tumor immunotherapy: the tumor cell as an antigen-presenting cell
Current Opinion in Immunology, 1994Increased knowledge in basic immunology has led to a variety of innovative and imaginative approaches for tumor-specific immunotherapy. One of these approaches is based on the premise that tumor cells do not normally stimulate an effective tumor-specific immune response, because they do not efficiently present tumor antigens to the relevant lymphocytes.
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2007
This chapter reviews the history of tumor cell vaccines, both autologous and allogeneic, as well as adjuvants used with tumor cell vaccines. The chapter discusses various tumor cell modifications that have been tested over the years. The immune response to tumor vaccines is briefly described, as are some methods of immune monitoring after vaccine ...
Patricia L, Thompson +1 more
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This chapter reviews the history of tumor cell vaccines, both autologous and allogeneic, as well as adjuvants used with tumor cell vaccines. The chapter discusses various tumor cell modifications that have been tested over the years. The immune response to tumor vaccines is briefly described, as are some methods of immune monitoring after vaccine ...
Patricia L, Thompson +1 more
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Clinical Orthopaedics and Related Research, 1986
Multiple myeloma and solitary plasmacytoma are common reticuloendothelial diseases. They involve primarily the bone marrow but have occasional extramedullary components. Numerous complications have been reported with these diseases. Despite modern modes of therapy, the prognosis remains grim. Myeloma and plasmacytoma are part of the continuum of B-Cell
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Multiple myeloma and solitary plasmacytoma are common reticuloendothelial diseases. They involve primarily the bone marrow but have occasional extramedullary components. Numerous complications have been reported with these diseases. Despite modern modes of therapy, the prognosis remains grim. Myeloma and plasmacytoma are part of the continuum of B-Cell
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Current Opinion in Oncology, 2005
This review provides an overview of some of the recent pre-clinical and clinical developments in germ cell tumors.Recent epidemiological studies highlight the variations in the geographic and ethnic distribution of germ cell tumors and the changing incidence of seminoma versus nonseminoma in the population. Additional studies are continuing to identify
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This review provides an overview of some of the recent pre-clinical and clinical developments in germ cell tumors.Recent epidemiological studies highlight the variations in the geographic and ethnic distribution of germ cell tumors and the changing incidence of seminoma versus nonseminoma in the population. Additional studies are continuing to identify
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Current Pharmaceutical Biotechnology, 2009
Cancer Stem cells (CSC) are defined as a population of cells found within a tumor that have characteristics similar to normal stem cells. Like normal stem cells they have the potential to self renew and differentiate. The cellular origin of these cancer stem cells--whether they originate from stem cells that have lost the ability to regulate ...
Nitu, Bansal, Debabrata, Banerjee
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Cancer Stem cells (CSC) are defined as a population of cells found within a tumor that have characteristics similar to normal stem cells. Like normal stem cells they have the potential to self renew and differentiate. The cellular origin of these cancer stem cells--whether they originate from stem cells that have lost the ability to regulate ...
Nitu, Bansal, Debabrata, Banerjee
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Annals of Otology, Rhinology & Laryngology, 1994
The skin and subcutaneous tissue and mucosae of the head and neck are areas of predilection for granular cell tumors. These often histogenetically enigmatic lesions have two principal clinicopathologic presentations: an infantile (congenital) epulis form of the gnathic gingiva and a noncongenital soft tissue and aerodigestive form.
M, Kershisnik, J G, Batsakis, B, Mackay
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The skin and subcutaneous tissue and mucosae of the head and neck are areas of predilection for granular cell tumors. These often histogenetically enigmatic lesions have two principal clinicopathologic presentations: an infantile (congenital) epulis form of the gnathic gingiva and a noncongenital soft tissue and aerodigestive form.
M, Kershisnik, J G, Batsakis, B, Mackay
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Nephron, 1978
A 15-year-old female with primary reninism presented with benign hypertension, normokalemia, normal aortagram and normal intravenous pyelogram. The diagnosis was suggested only by a remarkably elevated plasma renin activity (PRA). Selective catheterization of renal vein branches was necessary to make the diagnosis of a tumor.
G, Connor +5 more
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A 15-year-old female with primary reninism presented with benign hypertension, normokalemia, normal aortagram and normal intravenous pyelogram. The diagnosis was suggested only by a remarkably elevated plasma renin activity (PRA). Selective catheterization of renal vein branches was necessary to make the diagnosis of a tumor.
G, Connor +5 more
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