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Circulating Tumor Cells

Methods in Molecular Biology, 2017
In most solid tumors, it is distant metastases rather than the primary tumor which limit the prognosis. Distant metastases are caused by circulating tumor cells (CTCs) which actively invade the blood stream, attach to the endothelium in the target organ, invade the surrounding parenchyma, and form new tumors.
M. Magbanua, John W. Park
semanticscholar   +4 more sources

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid.

Science, 1983
Tumor ascites fluids from guinea pigs, hamsters, and mice contain activity that rapidly increases microvascular permeability. Similar activity is also secreted by these tumor cells and a variety of other tumor cell lines in vitro.
D. Senger   +5 more
semanticscholar   +1 more source

Germ cell tumors

Current Opinion in Oncology, 2005
This review provides an overview of some of the recent pre-clinical and clinical developments in germ cell tumors.Recent epidemiological studies highlight the variations in the geographic and ethnic distribution of germ cell tumors and the changing incidence of seminoma versus nonseminoma in the population. Additional studies are continuing to identify
openaire   +5 more sources

Tumor Initiating Cells

Current Pharmaceutical Biotechnology, 2009
Cancer Stem cells (CSC) are defined as a population of cells found within a tumor that have characteristics similar to normal stem cells. Like normal stem cells they have the potential to self renew and differentiate. The cellular origin of these cancer stem cells--whether they originate from stem cells that have lost the ability to regulate ...
Nitu Bansal, Debabrata Banerjee
openaire   +3 more sources

Granular Cell Tumors

Annals of Otology, Rhinology & Laryngology, 1994
The skin and subcutaneous tissue and mucosae of the head and neck are areas of predilection for granular cell tumors. These often histogenetically enigmatic lesions have two principal clinicopathologic presentations: an infantile (congenital) epulis form of the gnathic gingiva and a noncongenital soft tissue and aerodigestive form.
Matthew Kershisnik   +2 more
openaire   +3 more sources

Tumor immunotherapy: the tumor cell as an antigen-presenting cell

Current Opinion in Immunology, 1994
Increased knowledge in basic immunology has led to a variety of innovative and imaginative approaches for tumor-specific immunotherapy. One of these approaches is based on the premise that tumor cells do not normally stimulate an effective tumor-specific immune response, because they do not efficiently present tumor antigens to the relevant lymphocytes.
openaire   +3 more sources

Germ Cell Tumors [PDF]

open access: possibleSurgical Clinics of North America, 2006
The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
openaire   +2 more sources

H2O2-activatable and O2-evolving nanoparticles for highly efficient and selective photodynamic therapy against hypoxic tumor cells.

Journal of the American Chemical Society, 2015
The low selectivity of currently available photosensitizers, which causes the treatment-related toxicity and side effects on adjacent normal tissues, is a major limitation for clinical photodynamic therapy (PDT) against cancer.
Huachao Chen   +3 more
semanticscholar   +1 more source

Plasma Cell Tumors

Clinical Orthopaedics and Related Research, 1986
Multiple myeloma and solitary plasmacytoma are common reticuloendothelial diseases. They involve primarily the bone marrow but have occasional extramedullary components. Numerous complications have been reported with these diseases. Despite modern modes of therapy, the prognosis remains grim. Myeloma and plasmacytoma are part of the continuum of B-Cell
openaire   +3 more sources

Tumor cell metastasis

Critical Reviews in Oncology/Hematology, 1986
Local tissue invasion and the formation of metastatic lesions are characteristic properties of many malignant tumors. The formation of metastases is a complex process involving the passage of tumor cells from the site of the primary bulk tumor through successive connective tissue barriers, ultimately resulting in the growth of secondary tumor cell ...
Raymond M. Lyall   +4 more
openaire   +3 more sources

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