Results 31 to 40 of about 15,400,316 (399)

Interactions of asbestos-activated macrophages with an experimental fibrosarcoma [PDF]

open access: yes, 1983
Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect ...
A Ewing   +12 more
core   +2 more sources

Circulating tumor cells [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
A typical cancerous tumor contains millions or even billions of cells harboring genetic mutations driving them to grow, divide, and invade the local tissue in which they’re embedded. However, as the cells proliferate, they don’t all stay in the neighborhood.
openaire   +2 more sources

Clinical Significance of PD-L1 Status in Circulating Tumor Cells for Cancer Management during Immunotherapy

open access: yesBiomedicines, 2023
The approval of monoclonal antibodies against programmed death-ligand 1 (PD-L1) and programmed cell death protein (PD1) has changed the landscape of cancer treatment. To date, many immune checkpoint inhibitors (ICIs) have been approved by the FDA for the
Areti Strati   +3 more
doaj   +1 more source

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells

open access: yesInternational Journal of Molecular Sciences, 2019
Tumor cells possess a high metabolic plasticity, which drives them to switch on the anaerobic glycolysis and lactate production when challenged by hypoxia.
K. Urbańska, A. Orzechowski
semanticscholar   +1 more source

Steroid Cell Tumor

open access: yesSultan Qaboos University Medical Journal, 2008
NA
Abdul Al-Farsi, Ayman Al-Talib
openaire   +3 more sources

Junctional Adhesion Molecule-C Mediates the Recruitment of Embryonic-Endothelial Progenitor Cells to the Perivascular Niche during Tumor Angiogenesis [PDF]

open access: yes, 2020
The homing of Endothelial Progenitor Cells (EPCs) to tumor angiogenic sites has been described as a multistep process, involving adhesion, migration, incorporation and sprouting, for which the underlying molecular and cellular mechanisms are yet to be ...
Bieback, Karen   +6 more
core   +1 more source

Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]

open access: yes, 2018
Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico   +11 more
core   +1 more source

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

open access: yesJournal of Experimental Medicine, 2017
It is unclear whether PD-L1 on tumor cells is sufficient for tumor immune evasion or simply correlates with an inflamed tumor microenvironment. We used three mouse tumor models sensitive to PD-1 blockade to evaluate the significance of PD-L1 on tumor ...
Vikram R. Juneja   +7 more
semanticscholar   +1 more source

Unconventional Protein Secretion in Brain Tumors Biology: Enlightening the Mechanisms for Tumor Survival and Progression

open access: yesFrontiers in Cell and Developmental Biology, 2022
Non-canonical secretion pathways, collectively known as unconventional protein secretion (UPS), are alternative secretory mechanisms usually associated with stress-inducing conditions.
Rebeca Piatniczka Iglesia   +18 more
doaj   +1 more source

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