Results 31 to 40 of about 13,345,800 (332)

Method of Detecting and Targeting Mutations in Cancer [PDF]

, 2007
While there are many differences between tumor and non-tumor cells, the basic underlying distinction is in the DNA. Tumor cells harbor mutations, at least some of which are not present in non-tumor cells.
Byard Edwards
core   +2 more sources

Steroid Cell Tumor

Sultan Qaboos University Medical Journal, 2008
NA
Abdul Al-Farsi, Ayman Al-Talib
openaire   +3 more sources

Trafficking of T Cells into Tumors [PDF]

Cancer Research, 2014
AbstractT cells are a crucial component of the immune response to infection and cancer. In addition to coordinating immunity in lymphoid tissue, T cells play a vital role at the disease site, which relies on their efficient and specific trafficking capabilities.
Phillip K. Darcy, Clare Y Slaney, Clare Y Slaney, Michael H. Kershaw   +3 more
openaire   +3 more sources

Prognostic Significance of TWIST1, CD24, CD44, and ALDH1 Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients

Cells, 2019
(1) Background: The aim of the study was to evaluate the prognostic significance of EMT-associated (TWIST1) and stem-cell (SC) transcript (CD24, CD44, ALDH1) quantification in EpCAM+ circulating tumor cells (CTCs) of early breast cancer patients.
Areti Strati, Michail Nikolaou, Vassilis Georgoulias, Evi S. Lianidou   +3 more
doaj   +1 more source

Clinical Significance of PD-L1 Status in Circulating Tumor Cells for Cancer Management during Immunotherapy

Biomedicines, 2023
The approval of monoclonal antibodies against programmed death-ligand 1 (PD-L1) and programmed cell death protein (PD1) has changed the landscape of cancer treatment. To date, many immune checkpoint inhibitors (ICIs) have been approved by the FDA for the
Areti Strati, Panagiota Economopoulou, Evi Lianidou, Amanda Psyrri   +3 more
doaj   +1 more source

Interactions of asbestos-activated macrophages with an experimental fibrosarcoma [PDF]

, 1983
Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect ...
A Ewing, Ames B. N., Cohn Z. A., Davies P., Gabizon A., J M Davis, K Donaldson, K James, Keller R, Lowry 0., Pylev L. N., Raz A., Topping D. C.   +12 more
core   +2 more sources

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer [PDF]

, 2016
Tumor–stroma interactions contribute to tumorigenesis. Tumor cells can educate the stroma at primary and distant sites to facilitate the recruitment of heterogeneous populations of immature myeloid cells, known as myeloid-derived suppressor cells (MDSCs).
Ali Zamani, Andrea Wang-Gillam, Aude-Hélène Capietto, Barcellos-Hoff, Biancamaria Ricci, Bindea, Capietto, David B. Bumpass, David G. DeNardo, Fowler, Gabitass, Gabrilovich, Gabrilovich, Galon, Hamanishi, Katherine Weilbaecher, Li, Liu, Lucia D’Amico, MacDonald, Mace, Mahmoud, Melissa Meyer, Mitchem, Mundy-Bosse, Pinzone, Porembka, Roberta Faccio, Räsänen, Sahil Mahajan, Schreiber, Sheila A. Stewart, Tian, Trikha, Weilbaecher, Xinming Su, Yaccoby, Yamabuki, Yang, Zhang, Zhang, Zheng, Zhengfeng Yang, Zhu   +43 more
core   +2 more sources

Tumor Endothelial Cells [PDF]

Cold Spring Harbor Perspectives in Medicine, 2011
The vascular endothelium is a dynamic cellular “organ” that controls passage of nutrients into tissues, maintains the flow of blood, and regulates the trafficking of leukocytes. In tumors, factors such as hypoxia and chronic growth factor stimulation result in endothelial dysfunction.
openaire   +2 more sources

Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Cancer immunotherapy is a promising therapeutic intervention. However, complete and durable responses are seen in only a fraction of cancer patients.
E. Peranzoni, J. Lemoine, L. Vimeux, V. Feuillet, S. Barrin, Chahrazade Kantari-Mimoun, N. Bercovici, M. Guerin, J. Biton, Hanane Ouakrim, F. Régnier, A. Lupo, M. Alifano, D. Damotte, E. Donnadieu   +14 more
semanticscholar   +1 more source

Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy [PDF]

, 2017
Adhesion to extracellular matrix (ECM) is crucially important for survival of normal epithelial cells as detachment from ECM triggers specific apoptosis known as anoikis.
A C Belkina, B E Pearson, M Lavaei, N Rahimi, N Woolf, P A Bondzie, R D Meyer, V Chitalia   +7 more
core   +1 more source