Results 61 to 70 of about 87,711 (271)

Intraoperative tumor lysis syndrome in a giant teratoma: a case report

BMC Surgery, 2019
Background Tumor lysis syndrome is an unusual metabolic emergency in solid tumors. Perioperative occurrence of this syndrome is extremely rare but may have fatal consequences if not detected and treated on time.
Daniel Pindak, Katarina Rejlekova, Miroslav Tomas, Ramadan Aziri, Eva Rovenska, Judita Puskacova, Michal Mego   +6 more
doaj   +1 more source

Pembrolizumab‐axitinib‐induced tumor lysis syndrome in a patient with metastatic renal cancer

Clinical Case Reports, 2020
Tumor lysis syndrome is uncommon in solid tumors but with the use of immunotherapy (checkpoint inhibitors) their incidence is increasing. Physicians need to take adequate precautions while treating patients with immunotherapy.
Manan Shah, Sanjay Jain, Temidayo Abe, Phani Keerthi Surapaneni, Kapil Bhatia   +4 more
doaj   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Severe Spontaneous Acute Tumor Lysis Syndrome and Hypoglycemia in Patient with Germ Cell Tumor

, 2010
Tumor lysis syndrome has been observed in patients with bulky, treatment-sensitive tumors, in particular hematological malignancies, especially after medical treatment (chemotherapy, corticosteroids, radiation, hormonal agents, and biological response ...
Antonio Greco, Concetta Di Micco, Evaristo Maiello, Marco Sperandeo, Gianluigi Vendemiale, Angelo De Cata, Vito D'Alessandro, Celeste Clemente   +7 more
core   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Tumor lysis syndrome in premature infant prompting early resection of a large sacrococcygeal teratoma: a case report

BMC Pediatrics, 2023
Background Sacrococcygeal teratomas (SCTs) are the most common congenital neoplasm and often require resection soon after birth. There are rare reports of cardiac arrest during surgery due to manipulation of the tumor triggering secondary necrosis and ...
Aditi Dey, Rita Wyrebek, Loraine Torres, Danilo Escoto, Fauzia Shakeel, Jennifer Mayer   +5 more
doaj   +1 more source

Tumor Lysis Syndrome Due to Pembrolizumab Use in Metastatic Nasopharyngeal Carcinoma

In this case, we report tumor lysis syndrome (TLS) in a patient with metastatic nasopharyngeal carcinoma treated with pembrolizumab. There are only a few studies reporting the development of TLS associated with pembrolizumab, but this is the first report
ÇAĞLAR, ALPEREN AKANSEL, Mehmet Bilici, Alperen Akansel Çağlar, BÜYÜKBAYRAM, MEHMET EMİN, Aykut Turhan, TEKİN, SALİM BAŞOL, Zekeriya Hannarici, TURHAN, AYKUT, Salim Başol Tekin, ÇOBAN EŞDUR, PINAR, Mehmet Emin Büyükbayram, HANNARİCİ, ZEKERİYA, Pınar Çoban Eşdur, BİLİCİ, MEHMET   +13 more
core   +1 more source

A Rare Case of Tumor Lysis Syndrome

, 2015
INTRODUCTION Tumor lysis syndrome (TLS) is a metabolic disturbance caused by the destruction of rapidly dividing cancer cells following administration of cytotoxic chemotherapy.
Mainardi, MS4, Anne, Jianqing Lin, Okamoto, MD, Daniel, Daniel Okamoto, Anne Mainardi, Lin, MD, Jianqing   +5 more
core   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source