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Tumor marker pseudoprogression and immune-related cholangitis during conversion therapy for massive hepatocellular carcinoma: a case report [PDF]
Frontiers in ImmunologyCases with massive (diameter ≥10 cm) hepatocellular carcinomas (HCCs) are uncommon and typically have poor outcomes; however, conversion therapy offers a beacon of hope for remission in patients with massive unresectable HCCs. Recently, immune checkpoint
Xiaodong Zhang +8 more
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Myeloid suppressor cell depletion augments antitumor activity in lung cancer. [PDF]
, 2012 BackgroundMyeloid derived suppressor cells (MDSC) are important regulators of immune responses. We evaluated the mechanistic role of MDSC depletion on antigen presenting cell (APC), NK, T cell activities and therapeutic vaccination responses in murine ...
Dubinett, Steven +10 more
core +22 more sources
pH-Responsive DNA Motif: From Rational Design to Analytical Applications
Frontiers in Chemistry, 2021 pH-responsive DNA motifs have attracted substantial attention attributed to their high designability and versatility of DNA chemistry. Such DNA motifs typically exploit DNA secondary structures that exhibit pH response properties because of the presence ...
Lin Lin Zheng +5 more
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Tim-3 associated with apoptotic NK cells and disease activity in SLE
European Journal of Inflammation, 2021 T cell immunoglobulin and mucin domain-containing molecule-3 (Tim-3) has been found to play important roles in systemic lupus erythematosus (SLE), however, whether Tim-3 is involved in apoptosis of NK cells in SLE remains unknown. The proportion of CD3 −
Di Zhao, Xiao Yang, Jie Zhang, Yi Zhang
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Frontiers in Chemistry, 2021 Hypoxia is not only the reason of tumor metastasis but also enhances the spread of cancer cells from the original tumor site, which results in cancer recurrence.
Weicai Wang +4 more
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Molecular & Cellular Proteomics, 2003 Abstract One of the questions most frequently asked of physicians by patients concerns prognosis. Markers of solid tumors are the best prognosticators of the course of these tumors. The effect of these markers on the host will have a substantial impact on prognosis by affecting the performance status of the patient.
Anne-Sofie Schrohl +6 more
openaire +2 more sources
Aptamer Sensor Based on Hybrid Chain Reaction and CRISPR-Cas9 System for STX Detection
Chemosensors, 2023 In recent years, pollution incidents caused by red tide occur frequently, and the red tide biotoxins brought by it make the food safety problem of seafood become a difficult problem to be solved urgently, which has caused great damage to the mariculture ...
Qinguo Zhao, Guizhen Li, Xuemei Li
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Cancer Cell International, 2022 Objective The incidence of non-virus-related hepatocellular carcinoma (NV-HCC) in hepatocellular carcinoma (HCC) is steadily increasing. The aim of this study was to establish a prognostic model to evaluate the overall survival (OS) of NV-HCC patients ...
Yu Jiang +7 more
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Frontiers in Chemistry, 2023 Coronavirus pandemic has been a huge jeopardy to human health in various systems since it outbroke, early detection and prevention of further escalation has become a priority.
Qiuqi Zhang +4 more
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Frontiers in Cell and Developmental Biology, 2020 Gastric cancer (GC) is a significant public health burden worldwide, and cisplatin resistance is the leading cause for the failure of chemotherapy in this disease. Previous studies have revealed that HOXA transcript at the distal tip (HOTTIP) is involved
Rui Zhao +18 more
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