Results 231 to 240 of about 1,271,462 (341)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Choice of serum tumor markers in patients with small cell lung cancer: progastrin-releasing peptide, neuron-specific enolase, and carcinoembryonic antigen

, 2018
Lisi Huang, Haiyan Yan, Long-Qiao-Zi Sun, Ying Xu, Donghao Cai, Xiaohui Li, Xinliang Chen, Xiaohong Luo, Chunzhe Duan   +8 more
openalex   +1 more source

Clinical characteristics and analysis of cerebrospinal fluid biochemical, tumor markers and cytologic indices in 209 patients with meningeal carcinomatosis: a cross-sectional study. [PDF]

Front Oncol
Xu S, Huang C, Ye Y, Lai K, Lan S, Chen J.   +5 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Immunofluorescent analyses of tumor marker beta-III tubuilin expression in tumor and ajacent normal lung tissue derived from patients with non-small cell lung cancer

, 2016
I. A. Mamichev, Т. А. Богуш, E. A. Dudko, O. M. Ryabinina, А. Н. Гришанина, V. E. Kirsanov, B. E. Polotsky, М. М. Давыдов   +7 more
openalex   +2 more sources

A comparative analysis of tumor markers reveals EDA fibronectin as a promising target in high-grade serous ovarian cancer. [PDF]

J Ovarian Res
Piermattei A, De Luca R, Peissert F, Plüss L, Puca E, D'Alessandris N, Travaglino A, Sillano F, Pasciuto T, Giannarelli D, Zannoni GF, Fagotti A, Neri D, Scambia G, Buttarelli M, Nero C.   +15 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

BIOM-09. PROGNOSTIC AND PREDICTIVE MARKERS FOR OUTCOME IN PATIENTS WITH IDHMT TUMORS TREATED IN THE EORTC CATNON TRIAL ON ADJUVANT AND/OR CONCURRENT TEMOZOLOMIDE IN ANAPLASTIC ASTROCYTOMA [PDF]

Martin J. van den Bent, Santoesha Ghisai, Sara Erridge, Michael A. Vogelbaum, Anna K. Nowak, Marc Sanson, Alba A. Brandes, Wolfgang Wick, Paul M. Clément, Jean François Baurain, Warren Mason, Michael Weller, Kenneth Aldape, Helen Wheeler, Pieter Wesseling, Johan M. Kros, Mircea Tesileanu, Vassilis Golfinopoulos, B. Baumert, Youri Hoostrate, Thierry Gorlia, Pim J. French   +21 more
openalex   +1 more source

Tumor Markers in Pleural Fluid: A Comprehensive Study on Diagnostic Accuracy. [PDF]

Diagnostics (Basel)
Aleksiev V, Markov D, Bechev K.
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source