Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma [PDF]
, 2016 Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME).
Alvarez, Hector A. +13 more
core +1 more source
Relationship between protein biomarkers of chemotherapy response and microsatellite status, tumor mutational burden and PD-L1 expression in cancer patients. [PDF]
, 2020 Chemotherapy and checkpoint inhibitor immunotherapies are increasingly used in combinations. We determined associations between the presence of anti-PD-1/PD-L1 therapeutic biomarkers and protein markers of potential chemotherapy response.
Arguello, David +5 more
core +2 more sources
Frontiers in Chemistry, 2020 It is highly promising to design and develop efficient and economical electrocatalysts for oxygen evolution reaction (OER) in alkaline solution. In this work, we prepare FeCoNi sulfide composites (including FeS, Co3S4, and Ni3S4) derived from in situ ...
Wanqing Teng +6 more
doaj +1 more source
Leptin and leptin receptor expression as biomarkers for breast cancer: a retrospective study
BMC Cancer, 2023 Background Effective screening and treatment have reduced the number of women dying from breast cancer (BC). However, the long-term sequelae of BC treatment and psychosocial factors seriously affect the life quality of BC patients and survivors ...
Yan Wang +5 more
doaj +1 more source
DACH1 suppresses breast cancer as a negative regulator of CD44. [PDF]
, 2017 Dachshund homolog 1 (DACH1), a key cell fate determination factor, contributes to tumorigenesis, invasion, metastasis of human breast neoplasm. However, the exact molecular mechanisms for the anti-tumor roles of DACH1 in breast carcinoma are still lack ...
Kuang, Dong +6 more
core +2 more sources
Management of germ cell tumors in children: Approaches to cure [PDF]
, 2002 The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G. +4 more
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Serum CA 15.3, CEA and ESR Patterns in Breast Cancer
The International Journal of Biological Markers, 1997 Serum CA 15.3, CEA and ESR were longitudinally determined in 298 patients with breast cancer during postsurgical follow-up and/or therapy. Observation lasted until the death of the patient or at least for three years.
M. Rubach +3 more
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Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells. [PDF]
, 2014 IntroductionAlthough breast phyllodes tumors are rare, there is no effective therapy other than surgery. Little is known about their tumor biology.
Chou, Fen-Pi +9 more
core +3 more sources
Scientific Reports, 2021 The clinical utility of serum immunoglobulin free light chains (sFLC) in IgG4-related disease (IgG4-RD) is unknown. Herein we evaluated their association with clinical phenotypes, serology and activity in patients with IgG4-RD. Cross-sectional study that
Eduardo Martín-Nares +6 more
doaj +1 more source
Clinical Behaviour of Prostatic Specific Antigen and Prostatic Acid Phosphatase: A Comparative Study
The International Journal of Biological Markers, 1989 We assayed prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum levels in 1383 patients using a double antibody radioimmunoassay (RIA) I 125 .
J. Morote Robles +3 more
doaj +1 more source