In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells [PDF]
, 2015 Oncogenic signaling in melanocytes results in oncogene-induced senescence (OIS), a stable cell-cycle arrest frequently characterized by a bi- or multinuclear phenotype that is considered as a barrier to cancer progression.
Bröcker, E.-B. +12 more
core +8 more sources
Leptin and leptin receptor expression as biomarkers for breast cancer: a retrospective study
BMC Cancer, 2023 Background Effective screening and treatment have reduced the number of women dying from breast cancer (BC). However, the long-term sequelae of BC treatment and psychosocial factors seriously affect the life quality of BC patients and survivors ...
Yan Wang +5 more
doaj +1 more source
Frontiers in Chemistry, 2020 It is highly promising to design and develop efficient and economical electrocatalysts for oxygen evolution reaction (OER) in alkaline solution. In this work, we prepare FeCoNi sulfide composites (including FeS, Co3S4, and Ni3S4) derived from in situ ...
Wanqing Teng +6 more
doaj +1 more source
Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population [PDF]
, 2016 The identification of signaling pathways that affect the cancer stem-like phenotype may provide insights into therapeutic targets for combating embryonal rhabdomyosarcoma.
Ciccarelli, Carmela +10 more
core +9 more sources
Relationship between protein biomarkers of chemotherapy response and microsatellite status, tumor mutational burden and PD-L1 expression in cancer patients. [PDF]
, 2020 Chemotherapy and checkpoint inhibitor immunotherapies are increasingly used in combinations. We determined associations between the presence of anti-PD-1/PD-L1 therapeutic biomarkers and protein markers of potential chemotherapy response.
Arguello, David +5 more
core +2 more sources
Follow-up after curative resection for gastric cancer. Is it time to tailor it? [PDF]
, 2017 There is still no consensus on the follow-up frequency and regimen after curative resection for gastric cancer. Moreover, controversy exists regarding the utility of follow-up in improving survival, and the recommendations of experts and societies vary ...
Antolino, L +5 more
core +1 more source
Scientific Reports, 2021 The clinical utility of serum immunoglobulin free light chains (sFLC) in IgG4-related disease (IgG4-RD) is unknown. Herein we evaluated their association with clinical phenotypes, serology and activity in patients with IgG4-RD. Cross-sectional study that
Eduardo Martín-Nares +6 more
doaj +1 more source
Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells. [PDF]
, 2014 IntroductionAlthough breast phyllodes tumors are rare, there is no effective therapy other than surgery. Little is known about their tumor biology.
Chou, Fen-Pi +9 more
core +3 more sources
Serum CA 15.3, CEA and ESR Patterns in Breast Cancer
The International Journal of Biological Markers, 1997 Serum CA 15.3, CEA and ESR were longitudinally determined in 298 patients with breast cancer during postsurgical follow-up and/or therapy. Observation lasted until the death of the patient or at least for three years.
M. Rubach +3 more
doaj +1 more source
Scientific Reports, 2021 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Eduardo Martín‑Nares +6 more
doaj +1 more source