This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Tumor necrosis factor alpha as a potential marker for prostate cancer
Background: Prostate cancer is currently the most common cause of cancer death in men. The exact cause of developing prostate cancer is not known though inflammation, ageing, ethnicity and heredity are important factors involved in the initiation and ...
M. S. Ali+2 more
doaj +1 more source
Tumor necrosis factor alpha (TNF- [PDF]
WSTĘP. Czynnik martwicy guza a (TNF-a) jest cytokiną, która może się przyczyniać do powstawania zjawiska insulinooporności. Insulinooporność jest jednym z kluczowych patomechanizmów prowadzących do ujawnienia się cukrzycy typu 2.
Biłan, Andrzej+2 more
core +1 more source
Methanol Extract of Hydroclathrus clathratus Inhibits Production of Nitric Oxide, Prostaglandin E2 and Tumor Necrosis Factor-α in Lipopolysaccharidestimulated BV2 Microglial Cells via Inhibition of NF-κB Activity [PDF]
Purpose: Hydroclathrus clathratus is a brown marine seaweed known to possess anti-cancer, anti-herpetic, and anti-coagulant activities. The present study is aimed at investigating some anti-inflammatory effects of H.
Chol, YH+4 more
core +2 more sources
Mice deficient in tristetraprolin (TTP), the prototype of a family of CCCH zinc finger proteins, develop an inflammatory syndrome mediated by excess tumor necrosis factor alpha (TNF-α).
W. Lai+5 more
semanticscholar +1 more source
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source
Background: Chronic periodontitis is a bacterial infection that result in bone destruction associated with the increasing level of salivary tumor necrosis alpha and interleukin6 that affect Mother-infant bonding status.
Liqa S Hassan, Ban S Diab
doaj +1 more source
Acid-mediated tumor invasion: How does vasculature affect the growth characteristics? [PDF]
We study the growth of an implanted a-vascular tumor seed in two-dimensions based on a model where the mechanism of invasion is centered on tumor-induced acidification of the micro-environment and consequent death of normal cells. The spatial distribution of the acid density around the tumor is found using mean-field analysis.
arxiv
Tumor necrosis factor-alpha antitumor and immunomodulatory effects [PDF]
In the first part of this thesis we examined the possibilities of using the cytokine tumor necrosis factor-alpha (TNFcx) for the latter aproach. Although multiple studies have been performed regarding the antitumor action of TNFcx, it is still not ...
Scheringa, M. (Marcel)
core +1 more source
Methanol Extract of Polyopes lancifolius Inhibits the Expression of Pro-inflammatory Mediators in LPSstimulated BV2 Microglia Cells via Downregulation of the NF-κB Pathway [PDF]
Purpose: This study is aimed at identifying the anti-inflammatory mechanisms of a methanol extract of Polyopes lancifolius (MEPL) in lipopolysaccharide (LPS)-stimulated BV2 microglia cells.Methods: The expression of mRNA and protein were investigated RT ...
Choi, YH+5 more
core +2 more sources