Results 101 to 110 of about 693,338 (390)

Serum tumor necrosis factor alpha and C-reactive protein increase in breast cancer patients [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2018
Background: Breast cancer is now the second most commonly cancer diagnosed in women and remains the leading cause of cancer death among females in less developed countries.
Johnkennedy Nnodim   +2 more
doaj  

Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]

open access: yes, 2013
Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core   +3 more sources

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

open access: yesAdvanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez   +3 more
wiley   +1 more source

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light

open access: yesJournal of Experimental Medicine, 1990
Tumor necrosis factor alpha (TNF-alpha), in addition to being cytotoxic for certain tumor cells, has turned out as a multifunctional cytokine that is involved in the regulation of immunity and inflammation.
Andreas K6ck   +6 more
semanticscholar   +1 more source

Pancreatic cancer cachexia: a review of mechanisms and therapeutics. [PDF]

open access: yes, 2014
Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge.
Andrew Eugene Hendifar   +8 more
core   +2 more sources

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Factor de necrosis tumoral alfa en pacientes con preeclampsia a término y pretérmino

open access: yesAvances en Biomedicina, 2012
El objetivo de la investigación fue identificar y comparar las concentraciones de factor de necrosis tumoral alfa en pacientes con preeclampsia a término y pre-término. Se seleccionó un total de 50 pacientes.
Eduardo Reyna Villasmil   +5 more
doaj  

LEVELS OF TUMOR NECROSIS FACTOR ALPHA IN PATIENTS WITH ISCHEMIC STROKE

open access: yesМедицинская иммунология, 2019
Ischemic stroke is the most common form of brain stroke. It is associated with functional changes of various blood and bone marrow cell populations, altered release of various cytokines, chemokines, etc.
I. A. Prilutskaya, Yu. Ya. Kryuk
doaj   +1 more source

Identification of a tumor necrosis factor-responsive element in the tumor necrosis factor alpha gene

open access: yesJournal of Biological Chemistry, 1991
The regulation by tumor necrosis factor alpha (TNF) of its own promoter has been investigated by transient transfection and nuclear protein binding assays. In human K652 erythroleukemia cells TNF produced an 8-10-fold activation of the human TNF promoter linked to the chloramphenicol acetyltransferase gene.
Dale C. Leitman   +4 more
openaire   +3 more sources

Joule‐Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures

open access: yesAdvanced Functional Materials, EarlyView.
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na   +15 more
wiley   +1 more source

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