Results 191 to 200 of about 238,106 (335)

UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling

Advanced Science, EarlyView.
Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan, Xueman Chen, Huai Yu, Jianzhao Ruan, Jingliang Kang, Xiaoyu Nie, Yumei Cao, Su'an Tang, Changhai Ding   +8 more
wiley   +1 more source

A CLDN18.2‐Targeted Nanoplatform Manipulates Magnetic Hyperthermia Spatiotemporally for Synergistic Immunotherapy in Gastric Cancer

Advanced Science, EarlyView.
CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang, Hui Hui, Jing Han, Ting Guo, Yiding Wang, Lin Meng, Cong Chen, Jie He, Xiaoyong Guo, Fuyu Zhong, Hong Du, Jie Tian, Xiaofang Xing, Yang Du, Jiafu Ji   +14 more
wiley   +1 more source

A Tailored Hydrogel With Local Glycemia Management, Antioxidant Activity, and Photothermal Antibacterial Properties for Diabetic Wound Healing

Advanced Science, EarlyView.
A multifunctional wound dressing (ACG gels) with antioxidant, local glycocontrol, and antibacterial properties to promote diabetic wound healing. Au‐CeO2 dumbbells effectively eliminate ROS, protecting cells from oxidative stress‐induced damage while exhibiting significant near‐infrared photothermal antibacterial activity.
Bangguo Zhou, Yangying Duan, Wenhao Li, Tao Chen, Jincheng Wang, Manting Cao, Guohao Lin, Ke Yang, Zhangqi Lai, Wencheng Wu   +9 more
wiley   +1 more source

Gene sequence of feline tumor necrosis factor alpha

Nucleic Acids Research, 1990
Clarence A. Rawlings, Bradford W. Coffee, R A McGraw, Cynthia M. Otto, Roman T. Drews   +4 more
openaire   +4 more sources

Incidence and Risk Factors for Invasive Fungal Infections in Patients Initiating Tumor Necrosis Factor-Alpha Inhibitors for Inflammatory Bowel Disease and Rheumatoid Arthritis. [PDF]

Clin Infect Dis
Hennessee I, Benedict K, Bahr NC, Lipner SR, Gold JAW.   +4 more
europepmc   +1 more source

Unraveling the Role of Tumor Necrosis Factor-Alpha in Diabetic Peripheral Neuropathy: A Systematic Review and Meta-Analysis. [PDF]

Cureus, 2023
Sen A, Mohanraj PS, Ranjan A, Rajendran V, ArulVijayaVani S, Balan Y, Bansal A.   +6 more
europepmc   +1 more source

Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor- alpha secretion [PDF]

, 1994
Naoki Oyaizu, TW McCloskey, S Than, Ruixuan Hu, VS Kalyanaraman, Savita Pahwa   +5 more
openalex   +1 more source

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH

Advanced Science, EarlyView.
In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen, Zhaohua Cai, Danrui Xiao, Yiping Shi, Qingqing Xiao, Min Liang, Yangjing Jiang, Yijie Huang, Feng Liang, Guo Zhou, Fei Zhuang, Xia Wang, Huanhuan Huo, Liang Fang, Qin Shao, Ben He   +15 more
wiley   +1 more source

Conducting a real-world study of Tumor Necrosis factor-alpha inhibitors-induced Systemic Lupus Erythematosus based on the FAERS database. [PDF]

Sci Rep
He M, Yang J, Yan S, Shu Q, Liu PC.
europepmc   +1 more source

Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments] [PDF]

, 1990
E Holler, HJ Kolb, A Moller, J Kempeni, S Liesenfeld, H Pechumer, W Lehmacher, G Ruckdeschel, B Gleixner, C Riedner   +9 more
openalex   +1 more source