Results 111 to 120 of about 6,142,230 (303)

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation

Advanced Functional Materials, EarlyView.
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko, Djanira Rodrigues Negrão, Tanmay Gupta, Robert Jeng, Otavio Augusto Titton Dias, Maia Jaffer‐Diaz, Dinesh Christendat, Mohini Sain   +7 more
wiley   +1 more source

FXYD3 and TNFα mRNA Expression in Laryngeal Squamous Cell Carcinoma and their Correlation with Clinicopathologic Parameters

Middle East Journal of Cancer, 2016
Background: Because of its effect on speech and swallowing, laryngeal squamous cell carcinoma is a devastating disease which has been shown to have a poor survival rate.
Somayeh Dadras, Mahboobeh Razmkhah, Bijan Khademi, Mehdi Ansari, Ahmad Hosseini, Abbas Ghaderi   +5 more
doaj  

The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy

SVU - International Journal of Medical Sciences
Background: Diabetic nephropathy has become the main cause of renal failure, and furthermore, is associated with a dramatic increase in cardiovascular risk.
Alia KH Mahmoud , Muhammed Ahmed Abd El Moety , Amal Khalifa Ahmed, Samer A. El-Sawy   +3 more
doaj   +1 more source

Tumor Necrosis Factor Alpha In Preeclampsia

, 2013
Pre-eclampsia is one of the most frequent complications of pregnancy, however, little is known about its aetiology. Insufficient adaptation of the decidual and intramyometrial portions of the spiral arterioles in preeclampsia results in reduced utero-placental blood flow, leading to local placental hypoxia.
Fozia A Patigaroo, Siddiqui, Anwar H, Gulat, Rajiv, ZehraMohsin   +3 more
openaire   +2 more sources

Critical Coupling in Semi‐Trasparent Fano Resonators for Photothermal Converters

Advanced Functional Materials, EarlyView.
An ultrathin metal–insulator multilayer architecture is engineered to exploit Fano‐resonant critical coupling, completely suppressing optical reflectance while achieving a balanced 50:50 trade‐off between absorbance and transmittance. Upon laser excitation at resonance, the metamaterial generates intense localized heat (ΔT≈550∘C$\Delta T {\approx }550^\
Giuseppe Emanuele Lio, Giuseppe Nicoletta, Roberto Caputo, Antonio Ferraro   +3 more
wiley   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Evaluation of Lavandula officinalis Extract on Lymphocyte Proliferation and Tumor Necrosis Factor-alpha Production

Journal of Medicinal Plants, 2011
Background: Studies have demonstrated that plant extracts have various biological effects including immunomodulatory effect. Objective: In the present study, the immunomodulatory effects of Lavandula officinalis on lymphocyte proliferation and tumor ...
A Azadmehr, R Hajiaghaee, Sh Rezazadeh, A Afshari, M Kiani amin, B Baradaran, P Ebrahimi   +6 more
doaj  

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Association of tumor necrosis factor-α and -β gene polymorphisms in inflammatory bowel disease

, 2016
Ebtissam Saleh Al-Meghaiseeb,1 Abdulrahman A Al-Robayan,1 Mulfi Mubarak Al-Otaibi,1 Misbahul Arfin,2 Abdulrahman K Al-Asmari2 1Department of Gastroenterology, 2Research Centre, Prince Sultan Military Medical City, Riyadh, Saudi Arabia Abstract ...
Al-Asmari AK, Al-Meghaiseeb ES, Al-Robayan AA, Arfin M, Al-Otaibi MM   +4 more
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