Results 221 to 230 of about 288,730 (263)

Bioassay for Tumor Necrosis Factors-alpha and -beta

Molecular Biotechnology, 2000
Tumor necrosis factor (TNF) is a central cytokine in the pathogenesis of septic shock and other inflammatory states. Assay by immunoassay is convenient, but, because of circulating soluble receptors, does not accurately reflect biological activity of the cytokine.
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Four epitopes on tumor necrosis factor-alpha defined by murine anti-tumor necrosis factor-alpha monoclonal antibodies

Immunology Letters, 1994
Eight murine anti-TNF alpha monoclonal antibodies (mAb) were produced after immunization of BALB/c mice with rhTNF alpha. Six of these mAbs were able to neutralize cytotoxic activity of TNF alpha against L929 cells. Two other mAbs had no neutralizing effect. Epitope mapping studies were performed by ELISA and by using a BIAcore system (Pharmacia).
B, Karim, R, Béliard, J J, Huart, D, Bourel   +3 more
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Role of lipopolysaccharide and tumor necrosis factor-alpha in induction of hepatocyte necrosis

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1995
The occurrence of acute hepatic failure during systemic inflammatory response syndrome (SIRS) is related to the extent of hepatocyte (HC) damage and cell death resulting from necrosis or apoptosis. We hypothesized that proinflammatory mediators such as lipopolysaccharide (LPS) and tumor necrosis factor-alpha (TNF-alpha) can, either directly or ...
J H, Wang, H P, Redmond, R W, Watson, D, Bouchier-Hayes   +3 more
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Cardiodepression by tumor necrosis factor-alpha.

European cytokine network, 1999
Cardiodepressant effects of tumor necrosis factor-alpha (TNF-alpha have been documented in numerous experimental settings in vivo and in vitro. In vivo administration of TNF-alpha mimicks the cardiovascular pattern of sepsis including septic cardiomyopathy.
U, Müller-Werdan, H, Engelmann, K, Werdan   +2 more
openaire   +1 more source

[Tumor necrosis factor alpha. Biological aspects].

Giornale italiano di chemioterapia, 1989
Human Tumor Necrosis Factor-alpha (TNF-alpha) is a multifaceted cytokine mainly produced by activated monocytes or macrophages. Several recent studies have shown that TNF-alpha can exert a variety of in vitro and in vivo effects including: modulation of normal and malignant haemopoiesis, antineoplastic activity, activation of neutrophils, induction of ...
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Tumor Necrosis Factor Alpha

2012
Adamantios Arampatzis, Lida Mademli, Thomas Reilly, Mike I. Lambert, Laurent Bosquet, Jean-Paul Richalet, Thierry Busso, Bertrand Mettauer, Stéphane Gréciano, Bernard Geny, Faidon Magkos, Beat Knechtle   +11 more
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Tumor Necrosis Factor Alpha: Implications of Anesthesia on Cancers

Cancers, 2023
Zhi-Fu Wu, Shun-Ming Chan, Yi-Hsuan Huang   +2 more
exaly  

[Tumor necrosis factor-alpha (cachectin)].

Revista clinica espanola, 1989
Tumor necrosis factor (TNF) is liberated by macrophages in response to infection. It has different biological effects, namely cytotoxicity on some tumor cell lines, anorexia, hyperlipidemia, and decreases in protein synthesis. It favors immunological responses and produces necrosis of certain tumors.
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Effect of tumor necrosis factor alpha on mitogen-activated human B cells.

Journal of Experimental Medicine, 1987
Kehrl J H, Fauci A S
exaly  

Obesity, tumor necrosis factor-alpha and tumor necrosis factor-alpha −308 polymorphism in normal pregnancy

American Journal of Obstetrics and Gynecology, 2005
Jennifer Donnelly, Sharon Cooley, Joanna Balding, Ciaran Murphy, Tom Walsh, Owen Smith, Michael Geary, Corrina M.C. Mahon   +7 more
openaire   +1 more source