Balance between cell survival and death: a minimal quantitative model of tumor necrosis factor alpha cytotoxicity [PDF]
arXiv, 2009 Tumor Necrosis Factor alpha (TNF) initiates a complex series of biochemical events in the cell upon binding to its type R1 receptor (TNF-R1). Recent experimental work has unravelled the molecular regulation of the recruitment of initial signaling complexes that lead either to cell survival or death.
arxiv
Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
Mediators of Inflammation, 2014 Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
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Journal of Baghdad College of Dentistry, 2019 Background: Chronic periodontitis is a bacterial infection that result in bone destruction associated with the increasing level of salivary tumor necrosis alpha and interleukin6 that affect Mother-infant bonding status.
Liqa S Hassan, Ban S Diab
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Inducing phase-locking and chaos in cellular oscillators by modulating the driving stimuli [PDF]
arXiv, 2011 Inflammatory responses in eucaryotic cells are often associated with oscillations in the nuclear-cytoplasmic translocation of the transcription factor NF-kB. In most laboratory realizations, the oscillations are triggered by a cytokine stimulus, like the tumor necrosis factor alpha, applied as a step change to a steady level. Here we use a mathematical
arxiv
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat [PDF]
Journal of Pharmacology and Experimental Therapeutics 323(2):
488-498 (2007), 2007 Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-a (TNF-a) is involved in BBB injury and edema formation through a mechanism involving matrix metalloproteinase (MMP) upregulation. There is emerging evidence
arxiv
International Journal of COPD, 2008 Fanny WS Ko1, Ting-Fan Leung2, Gary WK Wong2, Jenny Ngai1, Kin W To1, Susanna Ng1, David SC Hui11Department of Medicine and Therapeutics; 2Department of Pediatrics, The Chinese University of Hong Kong, Hong KongBackground: Assessment of airway ...
Fanny WS Ko +5 more
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Factor de necrosis tumoral alfa en pacientes con preeclampsia a término y pretérmino
Avances en Biomedicina, 2012 El objetivo de la investigación fue identificar y comparar las concentraciones de factor de necrosis tumoral alfa en pacientes con preeclampsia a término y pre-término. Se seleccionó un total de 50 pacientes.
Eduardo Reyna Villasmil +5 more
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LEVELS OF TUMOR NECROSIS FACTOR ALPHA IN PATIENTS WITH ISCHEMIC STROKE
Медицинская иммунология, 2019 Ischemic stroke is the most common form of brain stroke. It is associated with functional changes of various blood and bone marrow cell populations, altered release of various cytokines, chemokines, etc.
I. A. Prilutskaya, Yu. Ya. Kryuk
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Acid-mediated tumor invasion: How does vasculature affect the growth characteristics? [PDF]
arXiv, 2004 We study the growth of an implanted a-vascular tumor seed in two-dimensions based on a model where the mechanism of invasion is centered on tumor-induced acidification of the micro-environment and consequent death of normal cells. The spatial distribution of the acid density around the tumor is found using mean-field analysis.
arxiv
Serum tumor necrosis factor alpha and C-reactive protein increase in breast cancer patients [PDF]
Al Ameen Journal of Medical Sciences, 2018 Background: Breast cancer is now the second most commonly cancer diagnosed in women and remains the leading cause of cancer death among females in less developed countries.
Johnkennedy Nnodim +2 more
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