Results 71 to 80 of about 29,503 (186)

Association of metabolic obesity phenotypes with cognitive decline in the ELSA‐Brasil study

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2849-2858, April 2026.
Abstract Aims To investigate the association between metabolic obesity phenotypes and cognitive decline and evaluate the potential mediating role of C‐reactive protein (CRP). Methods Longitudinal cohort study using three waves (2008–2019) of the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil).
Paulo Henrique Lazzaris Coelho, Natalia Gomes Gonçalves, Itamar S. Santos, Alessandra C. Goulart, Sandhi Maria Barreto, Luana Giatti, Paulo Caramelli, Paulo Andrade Lotufo, Isabela Martins Bensenor, Claudia Kimie Suemoto   +9 more
wiley   +1 more source

Blood Biomarkers of Uveal Melanoma: Current Perspectives

Clinical Ophthalmology, 2020
Manuel F Bande Rodríguez, 1, 2 Beatriz Fernandez Marta, 1 Nerea Lago Baameiro, 3 Maria Santiago-Varela, 1, 2 Paula Silva-Rodríguez, 2, 4 María Jose Blanco-Teijeiro, 1, 2 Maria Pardo Perez, 3 Antonio Piñeiro Ces 1, 2 1Unidad ...
Bande Rodríguez MF, Fernandez Marta B, Lago Baameiro N, Santiago-Varela M, Silva-Rodríguez P, Blanco-Teijeiro MJ, Pardo Perez M, Piñeiro Ces A   +7 more
doaj  

Targeting Oncogenic BRAF: Past, Present, and Future. [PDF]

, 2019
Identifying recurrent somatic genetic alterations of, and dependency on, the kinase BRAF has enabled a "precision medicine" paradigm to diagnose and treat BRAF-driven tumors.
Bivona, Trever G, Wu, Wei, Zaman, Aubhishek   +2 more
core   +1 more source

Acute systemic and energy metabolism responses to velocity‐based resistance training following an oral glucose load in individuals with excess body weight

Experimental Physiology, Volume 111, Issue 4, Page 1847-1860, 1 April 2026.
Abstract We investigated the acute metabolic effects of two velocity‐based resistance training (RT) protocols, differing in intra‐set velocity loss (VL) thresholds, on postprandial substrate oxidation and glycaemic responses following a 75 g oral glucose tolerance test in individuals with excess body weight.
Hugo Alejandro Carrillo‐Arango, Miguel Alejandro Atencio‐Osorio, Leidy Tatiana Ordoñez‐Mora, Baisuli Benitez‐Gómez, Robinson Ramírez‐Vélez, Mikel Izquierdo   +5 more
wiley   +1 more source

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas [PDF]

, 2018
DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response. We systematically analyzed somatic alterations to provide a comprehensive view of DDR deficiency across 33 cancer types.
Alvaro, Domenico, Andrew D, Cherniack, Bin, Feng, Bragazzi, MARIA CONSIGLIA, Cardinale, Vincenzo, Casey S, Greene, Chase, Miller, Chen, Wang, Christina, Yau, David A, Wheeler, Denise, Wolf, Eve, Shinbrot, Galen F, Gao, Gaudio, Eugenio, Gordon B, Mills, Gregory P, Way, Hai, Hu, Haoran, Chen, Hui, Shen, Huihui, Fan, Ilya, Shmulevich, Jianfang, Liu, John N, Weinstein, Lawrence A, Donehower, Lei, Li, Li, Ding, Linghua, Wang, Matthew H, Bailey, Michael T, Zimmermann, Mostafa, Karimi, Nyasha, Chambwe, Peilin, Jia, Peter W, Laird, Pora, Kim, Raymond J, Monnat, Rehan, Akbani, Shaojun, Zhang, Theo A, Knijnenburg, Yang, Shen, Yonghong, Xiao, Yuexin, Liu, Zhongming, Zhao   +41 more
core   +1 more source

From Synthesis to Therapeutics: Bioactive‐Coated Zein Nanoparticles in Drug Delivery

Biopolymers, Volume 117, Issue 2, March 2026.
ABSTRACT Polymeric zein nanoparticles (ZNP), derived from corn protein, are biodegradable drug carriers with high stability and low synthesis costs. Their amphiphilic nature allows efficient encapsulation of both hydrophilic and lipophilic drugs, making them promising for drug delivery.
Milena Ferreira de Lima, Andy Joel Taipe Huisa, Azael da Silva Neto, Clarice Beatriz Gonçalves Silva, Iago Dillion Lima Cavalcanti, Karolliny Barbosa de Araújo, Mariane Cajubá de Britto Lira‐Nogueira, Nereide Stela Santos Magalhães, Priscila Gubert   +8 more
wiley   +1 more source

Ultrasonido en tumores óseos como hallazgo inesperado: Elementos de sospecha y caracterización

Revista Chilena de Radiología
Resumen: Introducción. El aumento de volumen de las partes blandas puede ser estudiado con una variedad de técnicas, entre ellas destaca el ultrasonido de alta resolución (US) por su alta disponibilidad. Los tumores óseos son una causa muy infrecuente de
Carolina Whittle P, Nicolás Sánchez D, Giancarlo Schiappacasse F, Valeria Schonstedt G, Gina Baldassare P   +4 more
doaj   +1 more source

Cancer3D: understanding cancer mutations through protein structures. [PDF]

, 2014
The new era of cancer genomics is providing us with extensive knowledge of mutations and other alterations in cancer. The Cancer3D database at http://www.cancer3d.org gives an open and user-friendly way to analyze cancer missense mutations in the context
Godzik, Adam, Hrabe, Thomas, Porta-Pardo, Eduard   +2 more
core   +1 more source

Tumor pardo en esqueleto axial de dos pacientes con enfermedad renal crónica en diálisis

Acta Médica Colombiana, 2018
Los tumores pardos son una forma localizada de osteítis fibrosa no neoplásica, secundaria a hiperparatiroidismo (primario o secundario). Hacen parte de las alteraciones del metabolismo mineral y óseo de la enfermedad renal crónica (ERC). Se manifiestan como lesiones líticas, expansivas, asociadas a masas de tejidos blandos, que pueden estar localizadas
Carrillo-Bayona, Jorge Alberto, Agudelo-Cardona, Carlos Alberto, Muñoz-Díaz, Harold Ariel, Alvarado-Benavides, Ana María, Caicedo-Ramírez, Juliana Andrea, Zúñiga-Rodríguez, Eduardo Adolfo   +5 more
openaire   +4 more sources

Financial Toxicity in Patients With Breast Cancer Treated at Private Medicine Institutions in Brazil

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Financial toxicity (FT) refers to the negative impact of the financial burden of cancer diagnosis and treatment on patients' well‐being. With rising global costs of oncologic therapies, diagnostics, and supportive care, FT has become a key concern in cancer care, influencing adherence, quality of life, and outcomes.
Aline Cristini Vieira, Matheus Costa e Silva, Cristiano De Padua Souza, Luciana Castro Garcia Landeiro, Max Senna Mano   +4 more
wiley   +1 more source