Results 61 to 70 of about 29,503 (186)

Combination of Upadacitinib and Risankizumab in Refractory Crohn's Disease

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background and Aim Dual targeted therapies (DTT) are a promising off‐label approach for the treatment of refractory Crohn's disease (CD). Upadacitinib and risankizumab are approved for the treatment of moderate to severe CD. Our aim was to evaluate the effectiveness and safety of a combination of upadacitinib and risankizumab for refractory CD.
Clara Ramos‐Belinchon, Nikolas Plevris, Ian Arnott, Shahida Din, Jonathan Blackwell, Charlie W. Lees   +5 more
wiley   +1 more source

The Evolving Role of CD8+CD28- Immunosenescent T Cells in Cancer Immunology [PDF]

, 2019
Functional, tumor-specific CD8+ cytotoxic T lymphocytes drive the adaptive immune response to cancer. Thus, induction of their activity is the ultimate aim of all immunotherapies.
Dey, Mahua, Fetcko, Kaleigh, Henriquez, Mario, Huff, Wei X., Kwon, Jae Hyun   +4 more
core   +1 more source

Mechanobiology in Stem Cell‐Based Bioprinting

Cell Proliferation, Volume 59, Issue 5, May 2026.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source

Porocarcinoma ecrino en el dorso del pie

Revista de la Facultad de Ciencias Médicas de Córdoba
Objetivos: El porocarcinoma ecrino es un tumor anexial maligno, infrecuente, derivado de las glándulas sudoríparas ecrinas, con potencial metastásico. Afecta principalmente a personas de edad avanzada y su localización más frecuente es a nivel de cabeza
Juana Sanguinetti, Lía Salomé Abeledo, María Walker, Javier Anaya , Corina Busso   +4 more
doaj   +1 more source

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease [PDF]

, 2016
Previous studies showed that YAP1 is over-expressed in hepatocellular carcinoma (HCC). Here we observed higher expression of Yap1/Ctgf axis in dysplastic nodules and HCC chemically-induced in F344 rats, genetically susceptible to hepatocarcinogenesis ...
Avila, Matias A., Berasain, Carmen, Brozzetti, Stefania, Calvisi, Diego F., Daino, Lucia, Demartis, Maria I., Feo, Claudio F., Feo, Francesco, Latte, Gavinella, Pascale, Rosa M., Porcu, Alberto, Seddaiu, Maria A., Simile, Maria M., Tomasi, Maria L.   +13 more
core   +2 more sources

Tumores pardos de región maxilofacial en paciente con hiperparatiroidismo secundario

Revista Cubana de Medicina Militar, 2022
Introducción: Los tumores pardos ocasionados por hiperparatiroidismo, ya sea primario o secundario, son lesiones de tejido blando intraóseo vascularizado, que se presentan con mayor frecuencia en huesos largos; ocasionalmente, las lesiones llegan a ser periféricas y se localizan sobre procesos alveolares de maxilar y mandíbula.
Yoimar Deronceré-Columbié, Dilber Cedeño-Ramos   +1 more
openaire   +2 more sources

Tumores pardos múltiples en enfermedad renal crónica en paciente en hemodiálisis, a propósito de un caso

INSPILIP, 2023
La enfermedad renal crónica grados avanzados con y sin terapias de reemplazo renal presenta hiperparatiroidismo secundario a trastornos del metabolismo óseo y mineral lo que aumento las alteraciones esqueléticas, anemia y riesgo cardiovascular. Los niveles séricos de calcio, fósforo, paratohormona, hemoglobina y las imágenes diagnósticas, ayudan al ...
Wilmer Sanango Reinoso, Luis Saquicela Espinoza, Carmen Sevilla Rodríguez, Larry Torres Criollo, Edisson Bermeo Astudillo, Aida Valladarez Vázquez, Roberto Sanango Ortiz   +6 more
openaire   +1 more source

Chromaffin Versus Platelet Granules: What We Have Learned From Chromaffin Cells for Human Studies

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Chromaffin cells and platelets both utilize exocytosis to release biogenic amines stored within large dense‐core vesicles—specifically chromaffin granules (epinephrine) and δ‐granules (serotonin). While the chromaffin cell is the foundational model for studying the secretory pathway, platelets offer a highly accessible human cell source for clinical ...
Ricardo Borges
wiley   +1 more source

Melanoma maligno de coroides: a propósito de un caso

Correo Científico Médico, 2017
El melanoma maligno de coroides es el tumor intraocular primario más frecuente en la edad adulta. Su evolución clínica es muy variable y constituye un peligro potencial para la vida de las personas afectadas. Se presenta el caso de un paciente de 42 años,
Julio Alberto Fernández Soler, Jesús Enrique Fuentes Hidalgo, Marlene Orges Ramírez, Silvia Martínez Quintana, Teresita Serrano Fuentes   +4 more
doaj   +2 more sources

DNA damage stress: Cui prodest? [PDF]

, 2019
DNA is an entity shielded by mechanisms that maintain genomic stability and are essential for living cells; however, DNA is constantly subject to assaults from the environment throughout the cellular life span, making the genome susceptible to mutation ...
Cialfi, Samantha, Franchitto, Matteo, Palermo, Rocco, Talora, Claudio, Verma, Nagendra, Zonfrilli, Azzurra   +5 more
core   +1 more source