Results 101 to 110 of about 5,001,621 (350)
Rheumatologic Manifestations of Patients With Type B Insulin Resistance
Arthritis Care &Research, EarlyView.Objective
The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown +4 morewiley +1 more sourcePrevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data
Arthritis Care &Research, EarlyView.Objective
Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour +7 morewiley +1 more sourceAnti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1 [PDF]
, 2011 IL-1b and IL-18 are proinflammatory cytokines that contribute to renal immune complex disease, but whether IL-1b and IL-18 are mediators of intrinsic glomerular inflammation is unknown.Volker Vielhauer, Clemens D Cohen, Vielhauer, V, Lichtnekert Julia, Dan Muruve, Shrikant R. Mulay, Muruve, D, Ramanjaneyulu Allam, Maja T. Lindenmeyer, Lichtnekert, Julia, Hans-Joachim Anders, Lindenmeyer, M T, Cohen Clemens D., Kulkarni, Onkar P., Vielhauer, Volker, Muruve Dan, Kulkarni Onkar P., Maja T Lindenmeyer, Cohen, Clemens D., Ryu, Mi, Rupanagudi Khader Valli, Ryu Mi, Khader Valli Rupanagudi, Mulay Shrikant R., Ryu, M, Lindenmeyer, Maja T., Anders Hans-Joachim, Clemens D. Cohen, Cohen, C D, Onkar P Kulkarni, Shrikant R Mulay, Allam, R, Allam Ramanjaneyulu, Vielhauer Volker, Muruve, Dan, Rupanagudi, Khader Valli, Anders, Hans-Joachim, Mi Ryu, Lichtnekert, J, Mulay, Shrikant R., Allam, Ramanjaneyulu, Julia Lichtnekert, Lindenmeyer Maja T., Rupanagudi, K V, Mulay, S R, Kulkarni, O P, Anders, H J, Onkar P. Kulkarni +47 morecore +1 more sourceAssessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up
Arthritis Care &Research, EarlyView.Objective
The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani +10 morewiley +1 more sourceProteomic profiling of urinary proteins in renal cancer by surface enhanced laser desorption ionisation (SELDI) and neural-network analysis: Identification of key issues affecting potential clinical utility.
, 2003 Recent advances in proteomic profiling technologies, such as surface enhanced laser desorption ionization mass spectrometry, have allowed preliminary profiling and identification of tumor markers in biological fluids in several cancer types and ...Rogers, M. A., Noble, Jason, Clarke, Paul, Selby, P. J., Banks, R. E., Munro, N. P., Paul, A. +6 morecore β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia +11 morewiley +1 more sourceCorrecting the Shrinkage Effects of Formalin Fixation and Tissue Processing for Renal Tumors: toward Standardization of Pathological Reporting of Tumor Size
Journal of Cancer, 2015 Given the importance of correctly staging renal cell carcinomas, specific guidelines should be in place for tumor size measurement. While a standard means of renal tumor measurement has not been established, intuitively, tumor size should be based on ...Thu Tran, C. Sundaram, C. Bahler, J. Eble, David J. Grignon, M. F. Monn, Novae B. Simper, Liang Cheng +7 moresemanticscholar +1 more sourceHandling and staging of renal cell carcinoma the international society of urological pathology consensus (ISUP) conference recommendations
, 2013 The International Society of Urologic Pathology 2012 Consensus Conference on renal cancer, through working group 3, focused on the issues of staging and specimen handling of renal tumors.Martignoni G., Evans A., Montironi, Rodolfo, Bonsib, S.M., Rezaei K., Bonsib, Stephen M., Fajardo D., Cathro H., Lloreta J., Amin, Mahul B, Gupta N., Kida M., Grignon D. J., Shanks J., Srinivasan B., Griffiths D., Latour M., Montironi, R., Humphrey P., Abraham A., Nichols P., Osunkoya A., Delahunt, B, Murphy H., Grignon D.J., Pyda-Karwicka M., Van Der Kwast T., Fine S., Kristiansen G., Warren A., Delahunt B., Falzarano S., Tamboli P., Srigley, John R., Billis, A., Bostwick D., Ronchetti R., Iczkowski K., Trias I., Allan R., ,, Kench J., Nazeer T., Billis, Athanase, Hulsbergen-van de Kaa, C.A., Deng F.-M., Chen Y.-B., Samaratunga, H, Lopez-Beltran, A., the ISUP Renal Tumor Panel, Trpkov, K., Zhao J., Hirsch M., Amin, Mahul B., Tan P.H., Amin M. B., Bethwaite P., Egevad, Lars, Reuter V., Egevad, L., Lopez-Beltran, Antonio, Egevad, L,, Srigley J.R., Jones E., Lewin C., Sweet J., Argani P., Suzigan S., Ghayouri M., Lie K., Russell L., Nesi G., Vakar-Lopez F., Tickoo S., Srigley J. R., McHale T., Shen S., Tamboli, Pheroze, Cheville J., Wang C., Grignon, David J, Rioux-Leclercq N., Lopez Beltran A., Tamboli, P., Giannico G., Ahmed K., Shabaik A., Jufe L.I., Billis, A, Bonsib, Stephen M, Samaratunga H., Amin, MB, Huang W., Brimo F., Axcrona U., Petraki C., Tamboli, P, Gokden N., Samaratunga, H., Hes O., Shevchuk M., Hussein S., Maclean F., the members of the ISUP Renal Tumor Panel, Miller R., Billis A., Zynger D., Yilmaz A., Parwani A., Birbe R., Loftus B., Lopez-Beltran, A, Bonsib S.M., Perry-Keene J., Amin, M.B., Miyamoto H., Al Ahmadie H., Crist H., Hameed O., Cheng L., Ganji M., Robinson B., True L., Pan C.-C., Picken M., Adeniran A., Berney D., Egevad L., Nacey J., Epstein J., Montironi R., Ozagari A., Samaratunga, Hemamali, Moch H., Bonsib S. M., Fridman E., Lane Z., Furusato B., Rohan S., Bonsib, SM, Barry M., Baydar D., Tsuzuki T., Delahunt, B., Cohen C., Kunju L.P., et al., Cho Y.M., Magi-Galluzzi C., Shah R., Delprado W., Fadare O., Huang J., Grignon, David J., Olgac S., Trpkov, K, Jimenez R., Sibony M., Srigley, John R, Merino M., Chuang A.-Y., Netto G., Zhou M., McKenney J., Takahashi H., Srigley, J.R., Van De Kaa C.H., Orozco R., Trpkov, Kiril, Scarpelli M., Yao J., Delahunt, Brett, Amin M.B., Grignon, DJ, Begin L., Algaba F., Fleming S., O'Donnell M., Susani M., Grignon, D.J., Lopez-Beltran A., Trpkov K. +181 morecore +1 more sourceIntrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery
Advanced Functional Materials, EarlyView.An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging, Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent +14 morewiley +1 more source
