Results 161 to 170 of about 91,211 (282)

Safety of Clomiphene Citrate and Its Impact on Serum Tumor Markers in Hypogonadal Testicular Cancer Patients After Chemotherapy. [PDF]

Cureus
Wren J, Myre B, Halpern JA, Panken E, Bennett NE, Brannigan RE.   +5 more
europepmc   +1 more source

Clinical, genetic, and familial features of POT1 tumor predisposition syndrome

Cancer, Volume 132, Issue 4, 15 February 2026.
Abstract Background Protection of telomere 1 (POT1) tumor predisposition syndrome (POT1‐TPD) is a hereditary leukemia syndrome that is identified in ∼5% of patients with chronic lymphocytic leukemia (CLL) and is characterized by a predisposition to other cancers, including gliomas, melanomas, and angiosarcomas.
Courtney D. DiNardo, Jennifer Croden, Hiam M. Abdel‐Salam, Tapan Kadia, Matteo Molica, Alexandre Bazinet, Prithviraj Bose, Abhishek Maiti, Fadi Haddad, Jan Burger, Hagop Kantarjian, William Wierda, Nitin Jain, Alessandra Ferrajoli   +13 more
wiley   +1 more source

Integrating Classical Tumor Markers and Systemic Inflammatory Indices for Enhanced Biological Profiling in Testicular Neoplasms. [PDF]

Cureus
Portakal S, Cakiroglu B, Solak M.
europepmc   +1 more source

Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips

Advanced Biology, Volume 10, Issue 2, February 2026.
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck, Jeroen Bugter, Gizem Yorukoglu, Mina Kazemzadeh Dastjerd, Thomas E. Winkler   +4 more
wiley   +1 more source

Prenatally diagnosed intra-abdominal testicular teratoma managed with single-stage Fowler-Stephens orchiopexy postnatally: A case report and literature review. [PDF]

Exp Ther Med
Fang H, Peng G, Liu X, Wu S, Hua Y, Wei G, Zhang D.   +6 more
europepmc   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, Volume 13, Issue 9, 13 February 2026.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Retroperitoneal hibernoma mimicking a metastatic germ cell tumor: a case report and review of the literature. [PDF]

J Med Case Rep
Ben Rejeb S, Aloui M, Kouki N, Ben Romdhane Y, Rachdi H, Khouni H.   +5 more
europepmc   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

Advanced Science, Volume 13, Issue 7, 3 February 2026.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li, Xiaochen Zhang, Jiangwei Xia, Shuang Liu, Yushan Du, Sihan Li, Shukui Zhang, Yong Zhang, Fen Ji, Jianwei Jiao, Jingjing Zhang   +10 more
wiley   +1 more source

Transglutaminase 7 Silencing Inhibits Proliferation and Modulates Inflammatory and Apoptotic Markers in Testicular Germ Cell Tumors. [PDF]

Oncol Res
Altuwayjiri RS, Almami IS.
europepmc   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

Animal Research and One Health, Volume 4, Issue 1, Page 14-27, February 2026.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang, Ao Guo, Lin Zhang, Shengru Wu, Juan Du, Taiyong Yu   +5 more
wiley   +1 more source