Microsatellite Instability-High Somatic-Type Malignancy Arising From a Primary Retroperitoneal Germ Cell Tumor: A Case Report. [PDF]
ABSTRACT Introduction Immune checkpoint inhibitors have shown only limited clinical efficacy in germ cell tumors (GCTs), underscoring the need for predictive biomarkers such as microsatellite instability‐high (MSI‐high). We report a rare case of mixed‐type GCTs treated with chemotherapy, in which the somatic‐type malignancy (STM) component was found to
Hayashi G +8 more
europepmc +2 more sources
Nut Consumption and Sperm Quality in Healthy Men: Results From the Led‐Fertyl Study
ABSTRACT Background Nuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.
Estefanía Dávila‐Córdova +10 more
wiley +1 more source
A Hidden Neighbor: A Rare Benign Paratesticular Mass Presenting as a Testicular Tumor. [PDF]
Bakhshi G +4 more
europepmc +1 more source
Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source
Azoospermia, Atrophy, and Asymmetry: Unilateral Sertoli Cell Tumor as a Rare and Overlooked Cause of Male Infertility: A Case Report and Literature Review. [PDF]
Ali RN +7 more
europepmc +1 more source
[Juvenile granulosa cell tumor-Testicular tumor of the very young : Report of three cases and contemporary recommendations]. [PDF]
Haider M +3 more
europepmc +1 more source
Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan +10 more
wiley +1 more source
Adult Granulosa Cell Tumor With Low-Level Amplifications of <i>JAK2</i>, <i>ERBB3</i>, <i>CDK4</i>, and <i>MDM2</i>: A Rare Testicular Tumor. [PDF]
Moran C +6 more
europepmc +1 more source
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben +3 more
wiley +1 more source
Comparison of inflammation-based biomarkers in metastatic testicular cancer at initial diagnosis. [PDF]
Hacibey I +6 more
europepmc +1 more source

