Results 201 to 210 of about 1,289,245 (239)

Prepubertal Screening for Testicular Adrenal Rest Tumors in Boys with Classic Congenital Adrenal Hyperplasia: Emerging Evidence and Practical Implications. [PDF]

Children (Basel)
Ranieri A, Ferrari V, Ortolano R, Candela E, Bernardini L, Lanari M, Baronio F.   +6 more
europepmc   +1 more source

Protective Effects of Luteolin Against Cisplatin‐Induced Hepatic and Renal Toxicity: Biochemical and Cellular Evidence

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Cisplatin induces oxidative stress and hepatotoxicity, as evidenced by increased serum biomarkers and oxidative damage parameters. Luteolin, derived from Pistacia terebinthus, mitigates these effects by enhancing antioxidant defense systems and improving cell viability in cancer cell lines.
Özge Temiz, Suna Kizilyildirim, Tuba Ozdemir‐Sanci, Emine Terzi, Beyza Ecem Oz‐Bedir, Mehmet Akyuz, Hikmet Y. Cogun, Ferit Kargin, Tuba Aydin, Ahmet Cakir   +9 more
wiley   +1 more source

Investigation of the Protective Effect of <i>Centella asiatica</i> Against Doxorubicin-Induced Testicular Damage in Rats. [PDF]

Int J Mol Sci
Bedir F, Suleyman Z, Kocaturk H, Altay MS, Keskin Cimen F, Altuner D, Babayeva M, Suleyman H.   +7 more
europepmc   +1 more source

Obeticholic Acid and Edaravone Protect Against Cisplatin‐Induced Hepatotoxicity Through Modulation of Keap1/Nrf2/ARE, TNF‐α/NF‐κB, and AKT/GSK‐3β Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The graphical abstract explores the possible underlying molecular mechanisms of Obeticholic acid against hepatotoxicity induced by chemotherapy exposure. ABSTRACT Hepatotoxicity is one of the most crucial side effects of chemotherapy administration. Obeticholic acid (OCA) is a semisynthetic bile acid and farnesoid X receptor (FXR) agonist derived from ...
Fares E. M. Ali, Adel G. Bakr, Abdel‐Gawad S. Shalkami, Ehab A. M. El‐Shoura, Lamiaa Khalaf Ahmed, Ali F. Abd‐Elsalam, Ahmed A. N. Ahmed, Emad H. M. Hassanein   +7 more
wiley   +1 more source

Intra-abdominal torsion of a cryptorchid testicle associated with teratoma in a rabbit (<i>Oryctolagus cuniculus</i>): A case report. [PDF]

Vet Anim Sci
Jacik SCC, da Silva DL, de Souza AJS, Custódio VLM, Schiavi GDS, Guimarães KOP, Souto DPBM, Gomes LS, Moncayo JR.   +8 more
europepmc   +1 more source

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

MedComm, Volume 7, Issue 9, September 2026.
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng, Zhipeng Shen, Yuanfang Wu, Xingze Huang, Zhongyuan Zhang, Jiangyu Liu, Qichun Wei, Wenhao Chen, Ye Chen, Liang Xu   +9 more
wiley   +1 more source

Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease

MedComm, Volume 7, Issue 9, September 2026.
Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi, Dongping Yao, Chanjuan Dong, Xiao Tu, Guojian Liao, Mengfei Long, Yongmei Xie   +6 more
wiley   +1 more source

Metachronous solitary metastasis from left testicle seminoma presenting as a large intracranial tumor 4 years post-treatment: a case report and review of the literature. [PDF]

J Med Case Rep
Borghol W, Assaf A, Khaddour S, Karaja S, Barboura M, Barboura N, Chaar A, AlChawwaf AZ.   +7 more
europepmc   +1 more source

Digital Phenotyping of Physical Activity and Mortality in Cancer Survivors

MedComm – Future Medicine, Volume 5, Issue 3, September 2026.
The study analyzed wrist‐worn accelerometer data from 864 cancer survivors in the NHANES dataset (left panel). We identified three key digital phenotypes and their optimal thresholds for survival benefit: MIMS Volume (> 4945), Intensity (> 24), and Variability (> 2.4) (middle panel).
Yuanyou Li, Tianchen Niu, Zhongzheng Xiang, Junhan Zhao, Junjie Zhang, Lingjie Fan   +5 more
wiley   +1 more source

Thrombosed and calcified epididymal-vasal vascular structures mimicking a paratesticular mass: A case report. [PDF]

Urol Case Rep
Büyük A, Durgun MN, Çeküç OC, Bostan SA, Pehlivan Y.   +4 more
europepmc   +1 more source