Results 31 to 40 of about 57,172 (289)

Metastatic Potential of Small Testicular Germ Cell Tumors: Implications for Surveillance of Small Testicular Masses

European Urology Open Science, 2022
Incidental detection of urogenital tumors has increased in recent decades owing to the greater use of ultrasonography and cross-sectional imaging. For patients with low-risk prostate cancer or small renal masses, active surveillance represents a valid ...
Manolis Pratsinis, Christian Fankhauser, Katerina Pratsinis, Jörg Beyer, Emanuel Bührer, Richard Cathomas, Natalie Fischer, Thomas Hermanns, Anita Hirschi-Blickenstorfer, Jörn Kamradt, Luis Alex Kluth, Deborah Zihler, Walter Mingrone, Beat Müller, Tim Nestler, Sacha I. Rothschild, Bettina Seifert, Arnoud J. Templeton, Angelika Terbuch, Mark-Peter Ufen, Regina Woelky, Silke Gillessen, Christian Rothermundt   +22 more
doaj   +1 more source

Secondary testicular tumors [PDF]

Cancer, 1972
Secondary testicular neoplasms are rare. Review of approximately 24,000 autopsies done at Hines Veterans Administration Hospital revealed 15 cases of metastatic involvement of the testes for an incidence of 0.06%. Histologic appearance of the metastatic tumors was identical to the primary sites and involved the testicle either as nodules or diffuse ...
E J, Pienkos, V R, Jablokow
openaire   +2 more sources

Pituitary tumor-transforming gene expression is a prognostic marker for tumor recurrence in squamous cell carcinoma of the head and neck

, 2006
Background The proto-oncogene pituitary tumor-transforming gene (PTTG) has been shown to be abundantly overexpressed in a large variety of neoplasms likely promoting neo-vascularization and tumor invasiveness.
Solbach, Christine, Peters Silke, Eckerdt, Frank, Peters, Silke, Knecht, Rainald, Roller, Marc, Roller Marc, Eckerdt Frank, Solbach Christine, Knecht Rainald   +9 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Abstract 3703: A genomic characterization of testicular germ cell tumor immune microenvironment

, 2017
Testicular germ cell tumors (TGCT) are a histologically diverse set of tumors and the most common cancer type in young men. As part of the TCGA effort, we analyzed tumors from 133 patients including 4 patients with asynchronous double primary TGCTs (137 ...
Benjamin Vincent, Charles M. Perou, Daniel P. Hollern, Katie Hoadley, TCGA Testicular Germ Cell Tumor Analysis Working Group   +4 more
core   +1 more source

Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse [PDF]

, 2009
Follicle stimulating hormone (FSH) acts through the Sertoli cell to ensure normal testicular development and function. To identify transcriptional mechanisms through which FSH acts in the testis we have treated gonadotrophin-deficient hypogonadal (hpg ...
Abel, M.H., Lee, S., Charlton, H.M., O'Shaughnessy, P.J., Baban, D.   +4 more
core   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Testicular tumors in children

Sakarya Tıp Dergisi, 2013
Testicular tumors in children are rare. Teratomas and yolk sacs tumor are most testicular tumors in children. Masses of testicular tumors are often painless. These may be misdiagnosed as a hydrocel. Tumor markers and Ultrasound used in diagnosed.
Turan Yıldız
doaj   +1 more source

Intraperitoneal seeding of a testicular mixed germ cell tumor following spontaneous intraperitoneal mass rupture with associated anti-NMDA paraneoplastic encephalitis

Urology Case Reports, 2023
A 25-year-old male was admitted to the neurological intensive care unit for neurologic deterioration, likely caused by a paraneoplastic syndrome secondary to testicular malignancy.
Morgan B. Marshall, Kassandra Dindinger-Hill, Umang Swami, Stephanie Lyden, Alejandro Sanchez   +4 more
doaj   +1 more source

Neoplasia testicular de células germinativas: estudo retrospectivo de 57 casos. [PDF]

, 1997
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Merlim, Sérgio Eduardo
core