Results 31 to 40 of about 90,749 (281)

Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog. [PDF]

, 2011
Pluripotent stem cells (PSCs) hold significant promise in regenerative medicine due to their unlimited capacity for self-renewal and potential to differentiate into every cell type in the body. One major barrier to the use of PSCs is their potential risk
Banerjee, Utpal, Clark, Amander T, Jiao, Jing, Li, Xinmin, Lindgren, Anne G, Natsuhara, Kyle, Tian, E, Vincent, John J, Wu, Hong   +8 more
core   +3 more sources

Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study [PDF]

, 2018
Purpose In this multicenter study, we evaluated the cumulative burden of morbidity (CBM) among > 1,200 testicular cancer survivors and applied factor analysis to determine the co-occurrence of adverse health outcomes (AHOs).
AnnaLynn M. Williams, Christian Kollmannsberger, Chunkit Fung, Clair Beard, Darren R. Feldman, David J. Vaughn, Deepak M. Sahasrabudhe, Howard D. Sesso, Jeri Kim, Lawrence H. Einhorn, Lois B. Travis, Mohammad I. Abu Zaid, null null, Patrick O. Monahan, Robert A. Huddart, Robert J. Hamilton, Ryan Cook, Sarah L. Kerns, Shirin Ardeshir-Rouhani-Fard, Sophie D. Fossa, Timothy E. Stump   +20 more
core   +1 more source

Laparoscopic resection of prenatally detected intra-abdominal testicular teratoma: Report of a neonatal case

Journal of Pediatric Surgery Case Reports, 2017
Prenatal detection of intra-abdominal testicular tumor is rare. In this paper, we discuss the early laparoscopic resection of prenatally detected testicular tumor of a neonate.
Keigo Yada, Hiroki Ishibashi, Hiroki Mori, Mitsuo Shimada   +3 more
doaj   +1 more source

Prepubertal testicular tumors: Clinical characteristics and indications for testis-sparing surgery in a multicenter retrospective study

Journal of Pediatric Surgery Open
Objectives: We aimed to clarify the characteristics of prepubertal testicular tumors and evaluate the suitability of testis-sparing surgery (TSS) for benign prepubertal testicular tumors, with a focus on clinical outcomes and tumor-specific factors that ...
Shojiro Hanaki, Shuichi Katayama, Yasuo Nakahara, Soichi Nakada, Kohsuke Hitomi, Takeshi Asai, Shuichi Ishibashi, Tsutomu Kanagawa, Koji Aoyama   +8 more
doaj   +1 more source

Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies [PDF]

, 1993
In biological fluids, hCG and its free alpha- (hCG alpha) and beta-subunits (hCG beta), occur in multiple forms. These various forms differ at the molecular level primarily in glycosylation, but also differ in protein backbone modifications corresponding
Berger, Peter, Mann, Klaus, Schwarz, Siegfried, Spöttl, Gerald, Wick, Georg   +4 more
core   +1 more source

Prognostic features and markers for testicular cancer management

Indian Journal of Urology, 2010
Testicular neoplasm accounts for about 1% of all cancers in men. Over the last 40 years, the incidence of testicular cancer has increased in northern European male populations for unknown reasons.
Eddy S Leman, Mark L Gonzalgo
doaj   +1 more source

Metastatic Potential of Small Testicular Germ Cell Tumors: Implications for Surveillance of Small Testicular Masses

European Urology Open Science, 2022
Incidental detection of urogenital tumors has increased in recent decades owing to the greater use of ultrasonography and cross-sectional imaging. For patients with low-risk prostate cancer or small renal masses, active surveillance represents a valid ...
Manolis Pratsinis, Christian Fankhauser, Katerina Pratsinis, Jörg Beyer, Emanuel Bührer, Richard Cathomas, Natalie Fischer, Thomas Hermanns, Anita Hirschi-Blickenstorfer, Jörn Kamradt, Luis Alex Kluth, Deborah Zihler, Walter Mingrone, Beat Müller, Tim Nestler, Sacha I. Rothschild, Bettina Seifert, Arnoud J. Templeton, Angelika Terbuch, Mark-Peter Ufen, Regina Woelky, Silke Gillessen, Christian Rothermundt   +22 more
doaj   +1 more source

An unusual cause of gynaecomastia in a male [PDF]

, 2019
Summary: Beta-human chorionic gonadotropin (βhCG) is normally produced by syncytiotrophoblasts of the placenta during pregnancy and aids embryo implantation.
Bano, G, Beharry, N, Du Parcq, J, Hameed, A, Rehman, T   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source