Results 181 to 190 of about 3,141,404 (351)

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Overexpression of Interleukin-17 Modulates Responses to Marek’s Disease Virus Infection and Tumor Formation in Chickens [PDF]

Nitish Boodhoo, Katherine Blake, Fatemeh Fazel, Janan Shoja Doost, Shayan Sharif   +4 more
openalex   +1 more source

Hepatitis B, C, and D Virus Infections and AFP Tumor Marker Prevalence Among the Elderly Population in Mongolia: A Nationwide Survey [PDF]

, 2022
Davaalkham Dambadarjaa, Yerkyebulan Mukhtar, Tsogzolbaatar Enkh-Oyun, Ser-Od Khuyagaa, Angarmurun Dayan, Nandin-Erdene Oyunbileg, Oyu-Erdene Shagdarsuren, Gunchmaa Nyam, Yosikazu Nakamura, Masaharu Takahashi, Hiroaki Okamoto   +10 more
openalex   +1 more source

Skin tumor and papilloma virus infection.

Skin Cancer, 1989
openaire   +2 more sources

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

Does acute inflammation triggered by infection promote cancer progression? [PDF]

PLoS Biol
Valença-Pereira F, Johnson B, DeGregori J, Rincon M.   +3 more
europepmc   +1 more source

Association of Tumor Necrosis Factor-Alpha (TNF-α) With Hepatitis C Virus Infection: A Case-Control Study

Laith A.I.K. Al-Kaif, Osamah Rasheed Hameed, Massar Aamer Merza, Kazem Mehdi Kazem   +3 more
openalex   +1 more source

A Case of Life-Threatening Airway Obstruction Due to Epstein-Barr Virus–Associated Smooth Muscle Tumor With HIV Infection [PDF]

Yuka Kudo-Nagata, Kazuaki Fukushima, Taro Sugimoto, Tomotake Okuma, Takahiro Hozumi, Toru Motoi, Akifumi Imamura   +6 more
openalex   +1 more source

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

Advanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu   +9 more
wiley   +1 more source