From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]
, 2015 Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
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Research Models for Studying Vascular Calcification [PDF]
, 2020 Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen +4 more
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Tumoral calcinosis in the cervical spine: a case report and review of the literature
Journal of Medical Case Reports, 2017 Background Tumoral calcinosis is rarely located in spine. A 55-year-old Japanese woman with cervical tumoral calcinosis is presented, along with a review of the literature relating to tumoral calcinosis in the spine. We discussed the etiology, diagnosis,
Rui Guo +6 more
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Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia [PDF]
, 2016 The transgenic and knockout (KO) animals involving Fgf23 have been highly informative in defining novel aspects of mineral metabolism, but are limited by shortened lifespan, inability of spatial/temporal FGF23 control, and infertility of the global KO ...
Allen, Matthew R. +6 more
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Tumoral Calcinosis in Secondary Hyperparathyroidism
Philippine Journal of Otolaryngology Head and Neck Surgery, 2016 Objective: To report a case of tumoral calcinosis from secondary hyperparathyroidism and to describe its surgical management. Methods: Study Design: Case report Setting: Tertiary public university hospital Patient: One ...
Reinzi Luz S. Bautista +4 more
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Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions
Case Reports in Orthopedics, 2020 Tumoral calcinosis involving the spine is rare. The involvement of the thoracic spine is rarer than that of the cervical or lumbar spine. We report a case of thoracic tumoral calcinosis accompanied by vertebral fracture with increased concentrations of ...
Isamu Miura +6 more
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Nicotinamide treatment in a murine model of familial tumoral calcinosis reduces serum Fgf23 and raises heart calcium [PDF]
, 2014 Mutations in the GALNT3 gene result in familial tumoral calcinosis, characterized by persistent hyperphosphatemia and ectopic calcific masses in soft tissues.
Gray, Amie K. +3 more
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Dietary phosphate restriction normalizes biochemical and skeletal abnormalities in a murine model of tumoral calcinosis [PDF]
, 2011 Mutations in the GALNT3 gene cause tumoral calcinosis characterized by ectopic calcifications due to persistent hyperphosphatemia. We recently developed Galnt3 knockout mice in a mixed background, which had hyperphosphatemia with increased bone mineral ...
Allen, Matthew R. +4 more
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Annals of Internal Medicine: Clinical Cases, 2023 Tumoral calcinosis is a rare autosomal recessive disorder marked by lobulated soft tissue calcifications not associated with physiologic osteogenesis but rather phosphate metabolism dysregulation.
Derek T. Clar +2 more
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Huge tumoral calcinosis mimicking a sarcoma
Indian Journal of Pathology and Microbiology, 2019 Asha Sharad Shenoy +2 more
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