Drooling as a Red Flag: Insights From a Case Series in Severe Dermatomyositis With Literature Review
ABSTRACT Dermatomyositis (DM) is a rare idiopathic inflammatory disease characterized by progressive proximal muscle weakness and distinctive dermatologic manifestations. Although dysphagia is a recognized complication of oropharyngeal muscle involvement, drooling (sialorrhea) is infrequently described and may be a marker of severe disease.
Alireza Mirzamohamadi +9 more
wiley +1 more source
Anti‐MDA5 dermatomyositis presenting with pneumomediastinum and pneumopericardium in the setting of rapidly progressive interstitial lung disease. These air‐leak complications signal severe, uncontrolled pulmonary inflammation. Early recognition of cutaneous clues and prompt, multidisciplinary escalation of immunosuppression are critical to improving ...
Thomas Bond +3 more
wiley +1 more source
Background Tumoral calcinosis is an uncommon clinicopathological condition which is characterized by the formation of calcium salt deposition in intra-articular or peri-articular soft tissues.
Yang Sha +4 more
doaj +1 more source
Critical Evaluation of Methods for the Identification of Aneugens
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun +8 more
wiley +1 more source
Lesión quística calcificada periféricamente en el biceps femoral de un perro [PDF]
Un perro pastor alemán macho de 7 meses de edad se presentó a consulta por la aparición de un abultamiento marcado en los músculos flexores de la extremidad posterior derecha. El estado general era normal y no había otros síntomas.
Ginel, D. I. +3 more
core
N-glükosüülimise kaasasündinud defektid: kirjanduse ülevaade ja haigusjuhu kirjeldus [PDF]
Glükosüülimise kaasasündinud defektid on kiiresti kasvav, erinevaid elundisüsteeme haarav ainevahetushaiguste rühm. Glükosüülimine on valkude modifitseerimise protsess, mille tulemusel sünteesitakse glükoproteiin.
Joost, Kairit +3 more
core +2 more sources
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs [PDF]
O-Linked α-N-acetylgalactosamine (O-GalNAc) glycans constitute a major part of the human glycome. They are difficult to study because of the complex interplay of 20 distinct glycosyltransferase isoenzymes that initiate this form of glycosylation, the ...
Bertozzi, Carolyn R. +9 more
core +3 more sources
Free functional gracilis muscle transfer for reconstruction of massive ectopic calcification following a lower extremity fracture: a case report and overview of the literature [PDF]
We present a patient with massive posttraumatic ectopic calcification in the lower extremity. The patient complained of an increasing tender soft tissue mass with signs of acute inflammation and foot dorsiflexion weakness following a tibial fracture for ...
Bode, Beata +2 more
core
Diagnosis and management of pseudohypoparathyroidism and related disorders: first international Consensus Statement [PDF]
This Consensus Statement covers recommendations for the diagnosis and management of patients with pseudohypoparathyroidism (PHP) and related disorders, which comprise metabolic disorders characterized by physical findings that variably include short ...
Ahmed, S.F. (Sayed) +45 more
core +2 more sources
Ocular involvement in tumoral calcinosis
We report a 32-year-old male who presented with blurring of vision in the right eye since 1.5 years. He had history of swelling over the extensor surfaces of large joints which were migratory in nature.
Harsha Bhattacharjee +2 more
doaj +1 more source

