Results 131 to 140 of about 4,011,391 (378)

Tumors of the rib

open access: yesDiagnostic and Interventional Imaging, 2013
The authors propose a pictorial review illustrating the imaging features of chest wall tumors and their specific features that discusses the main differential diagnoses. This review is based on published information and on our own experience.
Ahmed Larbi   +5 more
openaire   +3 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Tumor isoimmunity [PDF]

open access: yesExperientia, 1958
Einige neue Ergebnisse auf dem Gebiete der Tumor-Immunitat werden mit der Literatur in Einklang gebracht, und eine Hypothese zur spontanen Tumorbildung wird vorgeschlagen. Ferner wird auf die Notwendigkeit eingegangen, bei Tumor-Isoimmunitats-Experimenten Spontantumoren zu verwenden an Stelle von lange transplantierten, vonin vitro entstandenen oder ...
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Estudio preliminar del tratamiento de úlceras crónicas con equivalentes cutáneos obtenidos por ingeniería de tejidos

open access: yesMedisur, 2015
Las úlceras de las extremidades inferiores son afecciones de incidencia y prevalencia elevada, cuya cronicidad y persistencia en hacer recidivas son dos de las características evolutivas más relevantes. A pesar de un tratamiento etiológico correcto, a lo
Francisco Antonio Arvelo Álvarez   +3 more
doaj   +2 more sources

Tracheal tumors

open access: yesThe Journal of the Japanese Association for Chest Surgery, 1996
Tumors of the airway can be classified into malignant (squamous and adenoidcystic) and low-grade or benign neoplasms. The most common tumors are squamous cancer and adenoidcystic, occurring in about equal numbers. Pre- and intraoperative evaluations are mandatory, along with strict attention to technical details and postoperative care.
openaire   +3 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

A delecção do gene TP53 e a acumulação do p53 (AB-240) são importantes na determinação do prognóstico no carcinoma urotelial da bexiga [PDF]

open access: yes, 2007
TP53 gene deletions or mutations were related to more aggressiveness in invasive and in situ bladder tumors. However, its prognostic value in the superficial ones is not well defined.
Amaro, Teresina   +6 more
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

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