Results 221 to 230 of about 4,011,391 (378)

Cáncer secundario de Tiroides (Primitivo: Hipenefroma)

Cirugía del Uruguay, 1985
Se presenta una serie de 7 casos de cáncer secunda• rio de tiroides cuyo origen corresponde a adenocarcinoma renal. Se hacen consideraciones sobre su presentación clinica como nódulos de tiroides con una marero y microscopia en todo igual al tumor ...
Roberto Estrugo, Nancy Toledo, Gustavo dos Santos   +2 more
doaj  

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Correlación anatomoecográfica de la infiltración tumoral parietal en el cáncer de recto

Cirugía del Uruguay, 1994
Entre noviembre del 89 y octubre del 91, se estudiaron 96 pacientes con patología rectal, por ecografía endoluminal. En ese período se evaluaron 63 tumores, con 40 casos que cumplieron con los criterios de inclusión que se publican en este trabajo.
William Fernández, Carlos Sarroca, José María Drago, María E Denis, Gustavo Fernández   +4 more
doaj  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Neoplasma de colon transverso Fistulizado en el ciego

Cirugía del Uruguay, 1988
Se presenta un neoplasma del colon transverso derecho flstulizado en el ciego, variedad anatómica poco frecuente en las estadísticas extranjera y nacional consultada, con un "Second look" a los 5 meses que no mostró diseminación metastásica y con buena ...
Aída Cresseri, Gonzalo Estapé, Héctor Scigliano   +2 more
doaj  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

OBSERVATIONS ON TUMORS OF THE KIDNEY REGION IN CHILDREN [PDF]

, 1920
Langley Porter
openalex   +1 more source

Fístula bilio-cutánea y doble fístula colecisto-digestiva de un regastrectomizado por cáncer gástrico

Cirugía del Uruguay, 1989
Un regastrectomizado por cáncer de muñón gástrico presentó una doble fístula colecisto-colónica precedida de un íleo-biliar y obstrucción por cuerpo extraño intraluminal que fue tratada con parto al colon.
José Praderi, Eneas Terra, Angeles Cassinasco, Eduardo Curuchet, José Palacio, Raúl Praderi   +5 more
doaj  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source