Results 311 to 320 of about 527,270 (344)
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Adrenocortical Tumorigenesis

Annals of the New York Academy of Sciences, 2006
Abstract:  Through the widespread use of imaging techniques with great sensitivity adrenal tumors are often diagnosed as an incidental finding. Although the majority of these adrenal lesions are benign and without evidence of endocrine activity or malignancy, hormone hypersecretion needs to be ruled out by specific tests.
Beuschlein, Felix, Reincke, Martin
openaire   +3 more sources

Autophagy and Tumorigenesis

2020
Tumour cells are derived from normal cells that undergo numerous genetic and epigenetic mutations under various stresses. This process involves changes in many intrinsic cellular mechanisms and in the microenvironment. Understanding the process is important for preventing tumorigenesis and tumour recurrence.
Wenting, Liu   +4 more
openaire   +2 more sources

Tumorigenesis by Cadmium

Oncology, 1972
A single dose of cadmium chloride (CdCl2) (0.02–0.03 mM/kg) given subcutaneously to mature male Wistar rats leads to rapid testicular necrosis and, subsequently, to the development of interstitial cell neoplasms. Testicular tissue containing these neoplasms transforms labeled progesterone in vitro to testosterone, but this transformation is less ...
O J, Lucis, R, Lucis, K, Aterman
openaire   +2 more sources

Thyroid Tumorigenesis

Hormone Research, 1994
Thyroid tumorigenesis is discussed in the context of the thyroid as a stable tissue, composed of differentiated cells, with a greater dissociation of control of growth from control of differentiation than is found in stem cell tissues. Experimental thyroid carcinogenesis regimes usually use mutagen exposure followed by induced growth.
openaire   +2 more sources

Telomerase and tumorigenesis

Cancer Letters, 2003
The unique biology of telomeres and telomerase plays important roles in many aspects of mammalian cell physiology. Over the past decade, several lines of evidence have confirmed that the maintenance of telomeres and telomerase participate actively in the pathogenesis of human cancer.
Kenkichi, Masutomi, William C, Hahn
openaire   +2 more sources

Foreign Body Tumorigenesis

CRC Critical Reviews in Toxicology, 1976
This review deals with factors and mechanisms involved in sarcoma development upon implantation of chemically inert foreign bodies. The topic is of importance regarding cancer in asbestosis or schistosomiasis, and also in view of increasing ise of artificial implants.
K. Gerhard Brand   +3 more
openaire   +2 more sources

MicroRNAs in Tumorigenesis

Current Pharmaceutical Biotechnology, 2007
Emerging evidence suggests a class of non-coding RNAs termed microRNAs (miRNAs) play a key role in cancer. Since their original discovery in C. elegans in 1993 it has become evident that miRNAs are responsible for an entirely new mechanism of post-transcriptional gene regulation.
Kai Ove, Skaftnesmo   +3 more
openaire   +2 more sources

Phosphatases and tumorigenesis

Current Opinion in Oncology, 1998
Phosphatases are regulatory enzymes that antagonize the action of kinases within the cell. An understanding of the contribution of kinases to cancer has emerged during the past two decades; however, our understanding of phosphatases in cancer has lagged behind.
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Experimental Testicular Tumorigenesis

Journal of Urology, 1962
L D, HUNT, B M, HARVARD, J F, GLENN
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