Results 91 to 100 of about 2,238,052 (265)
, 2015 Background: Thyroid neoplasias with oncocytic features represent a specific phenotype in non-medullary thyroidcancer, reflecting the unique biological phenomenon of mitochondrial hyperplasia in the cytoplasm. Oncocyticthyroid cells are characterized by a
Ivana Kurelac +5 more
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Pharmacological Management of Gastrointestinal Neuroendocrine Tumors
, 2022 Gastrointestinal Neuroendocrine tumors are a rare diverse group of tumors arising from the diffuse neuroendocrine system. In recent times the incidence and prevalence of these tumors have increased which has led to further investigations on the treatment
Lawrence, Janet
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Tumors of the Sacrum: Diagnosis, Management, and Surgical Techniques
, 2017 Latin for “sacred bone” and so named for its recurrent role in ancient Greek and Egyptian mythology [1], the os sacrum remains the subject of much discourse and scholarship in modern-day musculoskeletal oncology.
Newman, Eric T. +5 more
core +1 more source
Aerosolized BC-819 inhibits primary but not secondary lung cancer growth. [PDF]
, 2011 Despite numerous efforts, drug based treatments for patients suffering from lung cancer remains poor. As a promising alternative, we investigated the therapeutic potential of BC-819 for the treatment of lung cancer in mouse tumor models.
Corinna Pfeifer +26 more
core +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
All datasets of primary tumors, primary or metastatic sites of metastatic tumors used in this study
<p>All datasets of primary tumors, primary or metastatic sites of metastatic tumors used in this study</p ...
Xie jiajing
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
CLASSIFICATION FOR THYROID GLAND TUMORS (WHO, 2017): ATTENTION TO PROGNOSTIC FACTORS
Инновационная медицина Кубани, 2019 In this article we presented four main changes in the Classification for Thyroid Gland Tumors, the fourth revision (WHO, 2017) regarding the revision presented in 2004. The most essential of them are: 1) defining the «other encapsulated tumors of thyroid
O. N. Ponkina
doaj