Results 111 to 120 of about 2,706,111 (311)

Natural Killer cells in non-hematopoietic malignancies

Frontiers in Immunology, 2012
Natural killer (NK) cells belong to the innate immune system and were initially described functionallywise by their spontaneous cytotoxic potential against transformed or virus-infected cells.
Mélanie eDesbois, Sylvie eRusakiewicz, Clara eLocher, laurence eZitvogel, Nathalie eChaput   +4 more
doaj   +1 more source

The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis. [PDF]

, 2016
Synovial sarcomas are aggressive soft-tissue malignancies that express chromosomal translocation-generated fusion genes, SS18-SSX1 or SS18-SSX2 in most cases.
Barrott, JJ, Cairns, BR, Capecchi, MR, Ding, L, Haldar, M, Jin, H, Jones, KB, Langer, EM, Monument, MJ, Mosbruger, TL, Randall, RL, Wilson, RK, Xie, M, Zhu, J-F   +13 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

NK Cell Exhaustion

Frontiers in Immunology, 2017
Natural killer cells are important effector lymphocytes of the innate immune system, playing critical roles in antitumor and anti-infection host defense.
Jiacheng Bi, Zhigang Tian, Zhigang Tian
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Involvement of ACSM family genes in the reprogramming of lipid metabolism within tumors and their investigation as promising therapeutic targets

Frontiers in Cell and Developmental Biology
Metabolic reprogramming of tumor cells is an important feature of oncogenesis and progression, with lipid metabolism playing a key role in this process.
Ke-Xin Fang, Zi-Qi Li, Jin-Liang Dong, Ze Yu   +3 more
doaj   +1 more source

Role of diffusion-weighted image in differentiation between epidermoid cyst and other cerebellopontine angle masses

Medical Journal of Babylon, 2018
Background: Many masses can present in the cerebellopontine angle (CPA), and the magnetic resonance imaging (MRI) is essential in the diagnosis and differential diagnosis of these masses, and a complimentary advanced MRI technique such as diffusion ...
Dhemyaa Ali Farhan, Osamah Ayad Abdulsttar   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Liquid Biopsy’s Role in Head and Neck Tumors: Changing Paradigms in the Era of Precision Medicine

Diagnostics
In the era of precision medicine, liquid biopsy has become an indispensable tool in research and clinical diagnostics. This innovative molecular approach offers significant benefits in managing cancers, such as melanoma, colorectal cancer, lung cancer ...
Rudy N. Zalzal, Najla Fakhruddin, Rami Mahfouz   +2 more
doaj   +1 more source