Results 111 to 120 of about 2,065,105 (317)

All datasets of primary tumors, primary or metastatic sites of metastatic tumors used in this study

open access: yes
<p>All datasets of primary tumors, primary or metastatic sites of metastatic tumors used in this study</p ...
Xie jiajing
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

NK Cell Exhaustion

open access: yesFrontiers in Immunology, 2017
Natural killer cells are important effector lymphocytes of the innate immune system, playing critical roles in antitumor and anti-infection host defense.
Jiacheng Bi, Zhigang Tian, Zhigang Tian
doaj   +1 more source

Pharmacological Management of Gastrointestinal Neuroendocrine Tumors

open access: yes, 2022
Gastrointestinal Neuroendocrine tumors are a rare diverse group of tumors arising from the diffuse neuroendocrine system. In recent times the incidence and prevalence of these tumors have increased which has led to further investigations on the treatment
Lawrence, Janet
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Involvement of ACSM family genes in the reprogramming of lipid metabolism within tumors and their investigation as promising therapeutic targets

open access: yesFrontiers in Cell and Developmental Biology
Metabolic reprogramming of tumor cells is an important feature of oncogenesis and progression, with lipid metabolism playing a key role in this process.
Ke-Xin Fang   +3 more
doaj   +1 more source

Role of diffusion-weighted image in differentiation between epidermoid cyst and other cerebellopontine angle masses

open access: yesMedical Journal of Babylon, 2018
Background: Many masses can present in the cerebellopontine angle (CPA), and the magnetic resonance imaging (MRI) is essential in the diagnosis and differential diagnosis of these masses, and a complimentary advanced MRI technique such as diffusion ...
Dhemyaa Ali Farhan   +1 more
doaj   +1 more source

Conjunctival Melanocytic Tumors-New Developments

open access: yes, 2014
Melanocytic lesions of the conjunctiva represent a wide spectrum of tumors that include benign, premalignant, and malignant tumors. There are many ongoing arguments about the definition, classification, and therapeutic options of the conjunctival ...
Hülya Gökmen Soysal
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Liquid Biopsy’s Role in Head and Neck Tumors: Changing Paradigms in the Era of Precision Medicine

open access: yesDiagnostics
In the era of precision medicine, liquid biopsy has become an indispensable tool in research and clinical diagnostics. This innovative molecular approach offers significant benefits in managing cancers, such as melanoma, colorectal cancer, lung cancer ...
Rudy N. Zalzal   +2 more
doaj   +1 more source

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