Results 111 to 120 of about 2,238,052 (265)
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy
Advanced NanoBiomed ResearchPlatelets play a crucial role in tumor development through a bidirectional interaction with cancer cells. On one hand, platelets promote tumor proliferation, metastasis, and immune evasion; on the other, tumors can activate platelets, creating a feedback
Chunyu Bai +5 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
, 2015 The most common pediatric orbital malignancy in the developed countries is rhabdomyosarcoma. In the developing world, however, the most common orbital malignancies in the pediatric group are not primary malignant tumors, but rather secondary and ...
Karcioglu, Zeynel A +1 more
core +1 more source
, 2020 Vascular tumors of the joint are rare; they are defined as neoplastic proliferations of cells with endothelial phenotype that arise in periarticular structures, especially the synovium.
Rosenberg, Andrew E +3 more
core +1 more source
alimentaci´on parenteral en el neoplasma de esófago
Cirugía del Uruguay, 1980 Se analizan 31 casos de pacientes portadores de neoplasma de esófago que recibieron alimentación parentera1 durante su internación en sala de Cirugía General. No se registraron muertes ni complicaciones serias debTdas a la técnica.
Ricardo Voelker +2 more
doaj
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
. Gastrointestinal stromal tumors (GIST) are mesenchymal neoplasms of the gastrointestinal tract (GI)that are defined, in part, by the expression of CD117, a c?Kit proto?oncogene protein.
QI ZHANG +6 more
core