Results 111 to 120 of about 6,372,774 (389)

Insights into the realtionship between toll like receptors and gamma delta T cell responses

Frontiers in Immunology, 2014
The tumour microenvironment is an important aspect of cancer biology that contributes to tumour initiation, tumour progression and responses to therapy.
Asif Amin Dar, Rushikesh Sudam Patil, Shubhada Vivek Chiplunkar   +2 more
doaj   +1 more source

A glomus tumor

Journal of the Belgian Society of Radiology, 2015
A 54-year-old woman presented with a two-year-history of tenderness and cold sensitivity of the subungueal region of her 3 left finger. Physical examination revealed a pinkish red spot under the nail. Ultrasonography of the 3 left finger shows a well-delimited hypoechoic and hypervascularised mass in the subungueal area (Fig. A).
Ahmed Larbi, Benjamin Dallaudière, Olivier Barbier, P. Kulczycka, B. Vande Berg   +4 more
openaire   +6 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

EVALUATING THE THERAPEUTIC EFFICACY OF RESTORING WILD-TYPE P53 ACTIVITY IN P53-MUTANT TUMORS [PDF]

, 2017
The p53 transcription factor is the most frequently altered in human cancers usually via missense mutations that undermine its transcriptional activity. Clinically, TP53 mutations have been shown to be remarkably predictive of refractoriness to treatment,
Larsson, Connie A
core   +1 more source

Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]

, 2009
Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Baur, Dorothee M., Besig, Sophie, Braun, Thomas, Hoefler, Heinz, Langer, Rupert, Perren, Aurel, Prinz, Christian, Rad, Roland, Voland, Petra   +8 more
core   +2 more sources

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen. [PDF]

, 1990
Breaking the state of immunological unresponsiveness of tumor-bearing individuals to cancer is a prerequisite for active or passive tumor-specific immunotherapy.
Koeppen, H, Perdrizet, GA, Ross, SR, Schreiber, H, Singh, S, Stauss, HJ   +5 more
core  

A hybrid neural network – world cup optimization algorithm for melanoma detection

Open Medicine, 2018
One of the most dangerous cancers in humans is Melanoma. However, early detection of melanoma can help us to cure it completely. This paper presents a new efficient method to detect malignancy in melanoma via images.
Razmjooy Navid, Sheykhahmad Fatima Rashid, Ghadimi Noradin   +2 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source