Results 11 to 20 of about 6,547,471 (339)

The roles of extracellular vesicles in the development, microenvironment, anticancer drug resistance, and therapy of head and neck squamous cell carcinoma

Journal of Experimental & Clinical Cancer Research, 2021
Head and neck squamous cell carcinoma (HNSCC) is one of the main malignant tumours affecting human health, mainly due to delayed diagnosis and high invasiveness.
Xueying Wang, Junnan Guo, Pingyang Yu, Lunhua Guo, Xionghui Mao, Junrong Wang, Susheng Miao, Ji Sun   +7 more
doaj   +1 more source

Evaluation of the incidence of splenic hilar lymph node metastasis in patients operated on for esophagogastric junction cancer

Nowotwory, 2023
INTRODUCTION: The purpose of this study is to evaluate the effect of esophagogastric junction cancer (EGJC) staging on the risk of splenic hilar lymph node involvement. MATERIAL AND METHODS: 312 patients with EGJC after R0 surgery were analyzed; 118 (38%)
Tomasz Olesiński, Marek Szpakowski, Wojciech Każmierczak, Urszula Sulkowska, Andrzej Rutkowski   +4 more
doaj   +1 more source

Episcleral brachytherapy as an effective alternative in vasoproliferative tumors [PDF]

International Journal of Ophthalmology, 2018
The aim of this study is to assess the results of episcleral brachytherapy as treatment of retinal vasoproliferative tumors (RVTs) in a referral Intraocular Tumors Unit (ITU). A retrospective review of all patients diagnosed with vasoproliferative tumors
Marta Para Prieto, Maria Antonia Saornil, Jesús María de Frutos Baraja, Ciro García Álvarez, Patricia Diezhandino García, Francisco López Lara   +5 more
doaj   +1 more source

Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

Nature Communications, 2020
Immune checkpoint inhibitors have limited efficacy in tumors with lower mutational burden and non-permissive microenvironment. Here, the authors show that combining MEK inhibition with an agonist anti-CD40 immunostimulatory antibody improves antitumor ...
Daniel Baumann, Tanja Hägele, Julian Mochayedi, Jennifer Drebant, Caroline Vent, Sven Blobner, Julia Han Noll, Irena Nickel, Corinna Schumacher, Sophie Luise Boos, Aline Sophie Daniel, Susann Wendler, Michael Volkmar, Oliver Strobel, Rienk Offringa   +14 more
doaj   +1 more source

Management of Intracranial Metastases in EGFR-Mutated NSCLC: A Review of Literature following an Unusual Case Report

Case Reports in Oncological Medicine, 2021
The arrival of subsequent generations of tyrosine-kinase inhibitors (TKIs) has significantly broaden the EGFR-mutated lung cancer therapeutic landscape.
Víctor Albarrán, Javier Pozas, Juan José Soto, Jorge Esteban, Elena Corral, Yolanda Lage, Pablo Gajate, Pilar Garrido   +7 more
doaj   +1 more source

HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer [PDF]

, 2013
Introduction: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas
A Goldhirsch, A Hurtado, A Noske, AA Lazar, AC Wolff, Andre Robidoux, BM Müller, Bruno V Sinn, C Denkert, Carsten Denkert, Christine Solbach, CK Osborne, D Slamon, DG Altman, DJ Dabbs, EA Perez, EH Romond, FL Baehner, G Hennig, G Konecny, G Pentheroudakis, G von Minckwitz, G von Minckwitz, G von Minckwitz, Gunter von Minckwitz, H Joensuu, Hans Tesch, I Pinhel, J Baselga, J Baselga, Jan C Brase, Jens Huober, Judith Prinzler, K Bohmann, Keyur Mehta, Knut Engels, L Gianni, L Gianni, LM McShane, M Bonetti, M Dowsett, M Dowsett, M Filipits, M Untch, M Untch, M Untch, M Untch, Martin-Leo Hansmann, Mattea Reinisch, ME Hammond, Michael Untch, MJ Piccart-Gebhart, MP Fereshteh, PC Roche, Peter A Fasching, Ralf Kronenwett, S Johnston, S Paik, S Paik, Sibylle Loibl, Silvia Darb-Esfahani, T Lahusen, W Zhao   +62 more
core   +1 more source

Volume mismatch indicates tumors in paramedial bithalamic diseases: a retrospective study

Frontiers in Neurology, 2023
ObjectiveThis study aimed to investigate the diagnostic performance of volume mismatch sign on discriminating paramedial bithalamic tumors from non-tumors.MethodsIn this study, we recruited patients with tumors or non-tumors of the paramedial bithalamus.
Lu Su, Peiyi Gao, Peiyi Gao
doaj   +1 more source

Lacrimal gland tumors in Turkey: types, frequency, and outcomes. [PDF]

, 2018
AIM: To evaluate the clinical, radiological, and treatment features of lacrimal gland tumors. METHODS: Retrospective review of 99 eyes of 92 patients with lacrimal gland tumors diagnosed and managed in a single institution between January 1999 and March ...
Erden, Esra, Gündüz, Ahmet Kaan, Shields, Carol L., Yeşiltaş, Yağmur Seda   +3 more
core   +2 more sources

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2013-2017.

Neuro-Oncology, 2020
The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control (CDC) and National Cancer Institute (NCI), is the largest population-based registry focused exclusively on primary brain and other ...
Q. Ostrom, N. Patil, G. Cioffi, K. Waite, C. Kruchko, J. Barnholtz-Sloan   +5 more
semanticscholar   +1 more source

Development of a Transcription Factor-Based Prognostic Model for Predicting the Immune Status and Outcome in Pancreatic Adenocarcinoma

Journal of Immunology Research, 2022
Pancreatic adenocarcinoma (PAAD) is the most common primary malignancy of the pancreas. Growing studies indicate that transcription factors (TFs) are abnormally expressed in PAAD.
Xianbin Zhang, Li Li, Peng Liu, Yu Tian, Peng Gong   +4 more
doaj   +1 more source