Results 191 to 200 of about 5,905,711 (364)

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

Acta Neuropathologica, 2016
D. Louis, A. Perry, G. Reifenberger, A. Deimling, D. Figarella-Branger, W. Cavenee, H. Ohgaki, O. Wiestler, P. Kleihues, D. Ellison   +9 more
semanticscholar   +1 more source

Plasma‐activated media selectively induces apoptotic death via an orchestrated oxidative stress pathway in high‐grade serous ovarian cancer cells

Molecular Oncology, EarlyView.
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies, Raja Ganesen, John Toubia, Sung‐Ha Hong, Sushil Kumar KC, Martin K. Oehler, Carmela Ricciardelli, Endre J. Szili, Nirmal Robinson, Melissa R. Pitman   +9 more
wiley   +1 more source

Prótesis Parcial Obturatriz Paralelizada, en Paciente Oncológico

Odontoestomatología
Al enfrentarnos a casos que tienen relación con tumores de cabeza y cuello, hay que tener en cuenta la gran diversidad de presentaciones de las neoplasias, histopatología y topografía anatómica de las mismas.
Javier de Lima, Carlos Cabrera, Blanca Estrada Esquivel, Raúl Sánchez Rubio, Roberto Soler   +4 more
doaj  

Primary Malignant Endotracheal Tumor [PDF]

, 1905
DRS. JUDSON DALAND, Joseph McFarland
openalex   +1 more source

Loss of SETD2 in wild‐type VHL clear cell renal cell carcinoma sensitizes cells to STF‐62247 and leads to DNA damage, cell cycle arrest, and cell death characteristic of pyroptosis

Molecular Oncology, EarlyView.
Vulnerability to the small molecule STF‐62247 is observed in SETD2‐inactivated VHL‐positive clear cell renal cell carcinoma (ccRCC) cells. DNA damage and loss of CDC25A leads to cell cycle arrest in S phase. Cleavage of caspase‐3 (CASP3) and gasdermin E (GSDME) suggests cell death by pyroptosis.
Mathieu Johnson, Sandra Turcotte
wiley   +1 more source

A mathematical study of the interaction between oxygen and lactate in an in-vivo and in-vitro tumor [PDF]

arXiv
Micro-environmental acidity is a common feature of the tumor. One of the causes behind tumor acidity is lactate production by hypoxic cells of the tumor. Hypoxia is a direct result of the establishment of oxygen gradients. It is commonly observed in the tumor in an in-vitro experimental setup and also in-vivo situation.
arxiv  

Tumors of the Testis [PDF]

, 1946
Nathan B. Friedman, Robert A. Moore
openalex   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

Molecular Oncology, EarlyView.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto, Hege Marie Vedeld, Guro Elisabeth Lind, Marine Jeanmougin   +3 more
wiley   +1 more source

Metastatic tumors to the stomach: clinical and endoscopic features. [PDF]

, 2006
AIM: To evaluate the clinical and endoscopic patterns in a large series of patients with metastatic tumors in the stomach. METHODS: A total of 64 patients with gastric metastases from solid malignant tumors were retrospectively examined between 1990 and ...
DE PALMA, GIOVANNI DOMENICO, I. Simeoli, L. Iannone, M. Donisi, M. Rega, MASONE, STEFANIA, P. Addeo, PERSICO, GIOVANNI, V. Pilone   +8 more
core  

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

Molecular Oncology, EarlyView.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores, Diego M. Fernández‐Aroca, Cristina Garnés‐García, Andrés Domínguez‐Calvo, Jaime Jiménez‐Suárez, Sebastià Sabater, Pablo Fernández‐Aroca, Ignacio Andrés, Francisco J. Cimas, Guillermo de Cárcer, Borja Belandia, Ignacio Palmero, Pablo Huertas, María José Ruiz‐Hidalgo, Ricardo Sánchez‐Prieto   +14 more
wiley   +1 more source