Results 21 to 30 of about 3,330,839 (370)
Nature Communications, 2020 Immune checkpoint inhibitors have limited efficacy in tumors with lower mutational burden and non-permissive microenvironment. Here, the authors show that combining MEK inhibition with an agonist anti-CD40 immunostimulatory antibody improves antitumor ...
Daniel Baumann +14 more
doaj +1 more source
Case Reports in Oncological Medicine, 2021 The arrival of subsequent generations of tyrosine-kinase inhibitors (TKIs) has significantly broaden the EGFR-mutated lung cancer therapeutic landscape.
Víctor Albarrán +7 more
doaj +1 more source
Medicina, 2019 Background and Objectives: The tumor microenvironment has been widely implicated in tumorigenesis because it harbors tumor cells that interact with surrounding cells through the circulatory and lymphatic systems to influence the development and progression of cancer.
Arneth, Borros +1 more
openaire +4 more sources
Lacrimal gland tumors in Turkey: types, frequency, and outcomes. [PDF]
, 2018 AIM: To evaluate the clinical, radiological, and treatment features of lacrimal gland tumors. METHODS: Retrospective review of 99 eyes of 92 patients with lacrimal gland tumors diagnosed and managed in a single institution between January 1999 and March ...
Erden, Esra +3 more
core +2 more sources
HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer [PDF]
, 2013 Introduction: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas
A Goldhirsch +62 more
core +1 more source
Journal of Inherited Metabolic Disease, 2010 Contains fulltext : 87587.pdf (Publisher’s version ) (Closed access)
Janssen, M.C.H., Sevaux, R.G.L. de
openaire +3 more sources
Acta Neuropathologica Communications, 2019 The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this issue, we investigated the prognostic impact
Toru Umehara +20 more
doaj +1 more source
MR imaging for evaluation of lesions of the cranial vault: a pictorial essay [PDF]
Arquivos de Neuro-Psiquiatria, 2003 PURPOSE: A variety of diseases affect the calvaria. They may be identified clinically as palpable masses or incidentally in radiologic examinations. There are many diagnostic possibilities, including congenital, neoplastic, inflammatory and traumatic ...
Lázaro Amaral +5 more
doaj +1 more source
Oral haemangiomas. Series of two case reports and review of management
Journal of Family Medicine and Primary Care, 2022 Haemangiomas are one of the most common of all human birth defects and are based on vascular tissues. These lesions are mainly identified into two groups which are named as (a) capillary and (b) cavernous haemangioma.
Sonam Gupta +4 more
doaj +1 more source
Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]
, 2017 BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine +5 more
core +1 more source