Results 61 to 70 of about 6,547,471 (339)

Cryosurgery of hepatic diseases

open access: yesБюллетень сибирской медицины, 2006
Literature data are presented on the development of cryosurgery namely cryosurgery of hepatic diseases in Russia. Expe- rience of surgical diseases' clinics of the Siberian State Medical University in which issues of cryosurgery in focal and diffuse ...
B. I. Alperovich
doaj   +1 more source

HPV16 E6/E7 -based mRNA vaccine is therapeutic in mice bearing aggressive HPV-positive lesions

open access: yesFrontiers in Immunology, 2023
HPV (Human papillomavirus) affects 600,000 people worldwide each year. Almost all cervical cancers are associated with a past HPV infection. In particular, the positivity to the high-risk type HPV16 is detected in most of the invasive cervical cancers ...
Kun Zhou   +10 more
doaj   +1 more source

Metastasis to parotid gland from non Head and Neck tumors [PDF]

open access: yes, 2018
Most primary tumors spreading metastasis to the parotid gland are usually located in the head and neck region, nonetheless, rarely, parotid gland can also be the target of metastatic localization site of distant primary tumors.
Andrea, Ciorba   +9 more
core  

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Renal papillary carcinoma developed in a kidney transplant recipient with late IgA-nephropathy [PDF]

open access: yes, 2016
With improvements in immunosuppressive therapy, patient and graft survival in renal transplant recipients have been prolonged. Increasing donor age and patient survival rates have been related to an increase in the number of de novo tumors ...
BERLOCO, Pasquale Bartolomeo   +7 more
core   +1 more source

Tumor Mutational Burden as a Predictive Biomarker in Solid Tumors.

open access: yesCancer Discovery, 2020
Tumor mutational burden (TMB), defined as the number of somatic mutations per megabase of interrogated genomic sequence, varies across malignancies. Panel sequencing-based estimates of TMB have largely replaced whole-exome sequencing-derived TMB in the ...
D. Sha   +5 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Nanostructures as Photothermal Agents in Tumor Treatment [PDF]

open access: gold, 2022
Yuqian Chen   +4 more
openalex   +1 more source

Multifocality and recurrence risk: a quantitative model of field cancerization [PDF]

open access: yes, 2013
Primary tumors often emerge within genetically altered fields of premalignant cells that appear histologically normal but have a high chance of progression to malignancy. Clinical observations have suggested that these premalignant fields pose high risks
Foo, Jasmine, Leder, Kevin, Ryser, Marc
core   +1 more source

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