Results 61 to 70 of about 5,905,711 (364)
A microRNA expression signature of human solid tumors defines cancer gene targets
Small noncoding microRNAs (miRNAs) can contribute to cancer development and progression and are differentially expressed in normal tissues and cancers.
S. Volinia+17 more
semanticscholar +1 more source
Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]
PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R.+13 more
core +3 more sources
Elastic free energy drives the shape of prevascular solid tumors [PDF]
It is well established that the mechanical environment influences cell functions in health and disease. Here, we address how the mechanical environment influences tumor growth, in particular, the shape of solid tumors. In an in vitro tumor model, which isolates mechanical interactions between tumor cells and a hydrogel, we find that tumors grow as ...
arxiv +1 more source
Tumor growth with nutrients: stability of the tumor patches [PDF]
In this paper, we study a tumor growth model with nutrients. The contact inhibition for the tumor cells, presented in the model, results in the evolution of a congested tumor patch. We study the regularity of the tumor patch as the nutrients' diffusion strength $D$ diminishes.
arxiv
This study aims to elucidate the clinical and molecular characteristics, treatment outcomes and prognostic factors of patients with histone H3 K27-mutant diffuse midline glioma.
Nobuhide Hayashi+44 more
doaj +1 more source
IntroductionSocial support as a complex construct has a positive influence not only on a patient’s condition but also on the process of the patient’s emotional adjustment to cancer.
Snezana Corovic+14 more
doaj +1 more source
Role of magnetic resonance imaging in the detection and characterization of solid pancreatic nodules: an update [PDF]
Pancreatic ductal adenocarcinoma is the most common malignant tumor of the pancreas. The remaining pancreatic tumors are a diverse group of pancreatic neoplasms that comprises cystic pancreatic neoplasms, endocrine tumors and other uncommon pancreatic ...
Ansari, Najwa Al+5 more
core +1 more source
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.
BACKGROUND Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis of gastrointestinal stromal tumors. Imatinib mesylate, a selective tyrosine kinase inhibitor, has been shown in preclinical models and preliminary clinical
G. Demetri+20 more
semanticscholar +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Therapy for involuting infantile hemangioma: Propranolol effectiveness
Background/Objectives: The efficacy of propranolol as a treatment for infantile hemangiomas (IHs) has been documented. Until now, little has been written about the role of propranolol beyond the proliferation phase of IH.
Luz Orozco-Covarrubias+3 more
doaj +1 more source