Results 1 to 10 of about 1,360,599 (360)

Sensitive screening of single nucleotide polymorphisms in cell free DNA for diagnosis of gestational tumours

open access: yesnpj Genomic Medicine, 2022
Tumours expressing human chorionic gonadotropin (hCG), the majority of which are difficult to biopsy due to their vascularity, have disparate prognoses depending on their origin.
Geoffrey J. Maher   +15 more
doaj   +1 more source

Hilar Tumours [PDF]

open access: yesCanadian Journal of Gastroenterology, 2004
Tumours that involve the confluence of the bile ducts in the liver hilum provide a major therapeutic challenge. Adequate palliation requires relief of jaundice. Even though jaundice can be relieved if only 30% of the liver is drained, the presence of undrained bile ducts may result in pruritus and a continued risk of cholangitis and hepatic abscess ...
Costamagna G.   +3 more
openaire   +4 more sources

Synovial fluid pH is as specific as synovial leukocyte count but less sensitive for the diagnosis of chronic prosthetic joint infection

open access: yesJournal of Orthopaedics and Traumatology, 2022
Background Synovial fluid markers (synovial leukocyte count and differential) have been shown to be most accurate in diagnosing prosthetic joint infection (PJI).
Christoph Theil   +7 more
doaj   +1 more source

Human papillomavirus E6 and E7: What remains?

open access: yesTumour Virus Research, 2021
Decades of research on the human papillomavirus oncogenes, E6 and E7, have given us huge amounts of data on their expression, functions and structures.
Arushi Vats   +3 more
doaj   +1 more source

Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]

open access: yes, 2020
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I   +3 more
core   +2 more sources

Multi-mode biodegradable tumour-microenvironment sensitive nanoparticles for targeted breast cancer imaging

open access: yesNanoscale Research Letters, 2020
Gas-filled ultrasound (US) contrast agents easily collapse in the body, and the gas can easily overflow, which limits the effectiveness of US imaging. To address this issue, an injectable gas-generating multi-mode system was developed that carries the MR
Zhenhui Nie   +5 more
doaj   +1 more source

Glomus tumour [PDF]

open access: yesThe Annals of The Royal College of Surgeons of England, 2016
Glomus tumours are rare tumours accounting for only 1–5% of soft tissue tumours of the hand. They are described classically in the subungual region. We present the case of a 32-year-old woman with a late diagnosis of a glomus tumour that had caused her excruciating pain. Clinical examination was positive for Hildreth’s sign and the Love test. Magnetic
C, Sethu, A U, Sethu
openaire   +2 more sources

Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. [PDF]

open access: yes, 2019
Solid tumours are infiltrated by effector T cells with the potential to control or reject them, as well as by regulatory T (Treg) cells that restrict the function of effector T cells and thereby promote tumour growth1.
Cadilha, Bruno L   +16 more
core   +2 more sources

Hypoxia in the Initiation and Progression of Neuroblastoma Tumours [PDF]

open access: yes, 2020
Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to ...
Gómez Muñoz, María Ángeles   +3 more
core   +1 more source

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition [PDF]

open access: yes, 2014
Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage.
A Micheli   +27 more
core   +4 more sources

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