Results 51 to 60 of about 1,360,599 (360)

Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]

, 2018
The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B., Hodgson, Joseph A., Parvy, Jean-Philippe   +2 more
core   +3 more sources

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source

Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer [PDF]

, 2017
background: The present study aimed to examine the relationship between tumour invasiveness (T stage), the local and systemic environment and cancer-specific survival (CSS) of patients with primary operable colorectal cancer.
A Chrysanthopoulou, A Huijbers, AJ Munro, B Mlecnik, C Guastadisegni, C S D Roxburgh, CE Dukes, CH Richards, D C McMillan, D Church, D Hanahan, DC McMillan, F Pages, F Pages, FA Sinicrope, G Bindea, GJ Guthrie, H Ueno, H Ueno, H van Wyk, HC van Wyk, ID Nagtegaal, J Edwards, J Galon, J Guinney, J H Park, J Li, JB O'Connell, JH Park, JH Park, JH Park, JH Park, K Birkenkamp-Demtroder, K Klintrup, L De Smedt, LL Gunderson, LS Rozek, MJ Pollheimer, P G Horgan, P Quirke, R Salazar, S Ogino, SA Vayrynen, SS McAllister, T Kantola, VH Koelzer, W De Roock, WE Mesker   +47 more
core   +1 more source

Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells [PDF]

, 2020
Retinoid treatment is employed during residual disease treatment in neuroblastoma, where the aim is to induce neural differentiation or death in tumour cells.
Bilip, Maja, Di Florio, Alessia, Eaton, Simon, Hart, Stephen L., Irving, Elsa, Maeshima, Ruhina, Mathiyalakan, Mayuran, Orford, Michael, Shah, Shreya, Simons, Claire, Stoker, Andrew W., Tagalakis, Aristides D.   +11 more
core   +4 more sources

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma

Scientific Reports, 2019
Three of the hallmarks of poor prognosis in paediatric ependymoma are drug resistance, local invasion and recurrence. We hypothesised that these hallmarks were due to the presence of a sub-population of cancer stem cells expressing the multi-drug efflux ...
Durgagauri H. Sabnis, Lisa C. D. Storer, Jo-Fen Liu, Hannah K. Jackson, J. P. Kilday, Richard G. Grundy, Ian D. Kerr, Beth Coyle   +7 more
doaj   +1 more source

Surface Expression of Precursor N-cadherin Promotes Tumor Cell Invasion

Neoplasia: An International Journal for Oncology Research, 2010
The expression of N-cadherin (NCAD) has been shown to correlate with increased tumor cell motility and metastasis. However, NCAD-mediated adhesion is a robust phenomenon and therefore seems to be inconsistent with the “release” from intercellular ...
Deborah Maret, Eugenia Gruzglin, Mohamad Seyed Sadr, Vincent Siu, Weisong Shan, Alexander W. Koch, Nabil G. Seidah, Rolando F. Del Maestro, David R. Colman   +8 more
doaj   +1 more source

The role of exosomes in the promotion of epithelial-to-mesenchymal transition and metastasis

Frontiers in Bioscience-Landmark, 2020
The progression of a solid cancer from a localised disease to metastatic stages is a key reason for mortality in patients. Amongst the drivers of cancer progression, Epithelial-to-Mesenchymal Transition (EMT) has been shown to be of crucial importance ...
Kekoolani S Visan,, Richard J Lobb,, Andreas Moller   +2 more
doaj   +1 more source

The optimal intravesical maintenance chemotherapy scheme for the intermediate-risk group non-muscle-invasive bladder cancer

BMC Cancer, 2023
Objective Although the current European Association of Urology(EAU) guideline recommends that patients with intermediate-risk non-muscle-invasive bladder cancer (NMIBC) should accept intravesical chemotherapy or Calmette-Guerin (BCG) for no more than one
Jian-Xin Chen, Wen-Ting Huang, Qing-Yun Zhang, Cheng-En Deng, Jue-ling Wei, Yuan-Liang Xie, Rui Lin, Guan-Zheng Feng, Guang-Lin Yang, Jun Long, Hao-Yuan Lu, Zeng-nan Mo   +11 more
doaj   +1 more source

Bone marrow impairment during early [177Lu]PSMA-617 radioligand therapy: Haematotoxicity or tumour progression? [PDF]

, 2022
Felix Kind, Kerstin Michalski, Elham Yousefzadeh‐Nowshahr, Philipp T. Meyer, Michael Mix, Juri Ruf   +5 more
openalex   +1 more source