Injury to the tunica media initiates atherogenesis in the presence of hyperlipidemia. [PDF]
Background and aimsFatty streaks initiating the formation of atheromatous plaque appear in the tunica intima. The tunica media is not known to be a nidus for lipid accumulation initiating atherogenesis. We assessed changes to the tunica media in response
Belhoul-Fakir H+13 more
europepmc +6 more sources
Assessment of the aortic tunica media histological changes in relation with the cause of death. [PDF]
The authors set out to evaluate the correlations between three of the main morphological aortic parameters (elastic fibers - FE, collagen fibers - FCOL, and smooth muscle fibers - FM) and the cause of death.Study groups included 25 cases died of a vascular disease (V_P), 37 cases died of a non-vascular disease (NV_P) and 28 cases died of a violent ...
Şeicaru DA+5 more
europepmc +3 more sources
Tunica intima compensation for reduced stiffness of the tunica media in aging renal arteries as measured with scanning acoustic microscopy. [PDF]
AbstractObjectivesAging causes stiffness and decreased function of the renal artery (RA). Histological study with light microscopy can reveal microscopic structural remodeling but no functional changes. The present study aimed to clarify the association between structural and functional aging of the RA through the use of scanning acoustic microscopy ...
Miura K.
europepmc +6 more sources
A cell-based mechanical model of coronary artery tunica media. [PDF]
A three-dimensional cell-based mechanical model of coronary artery tunica media is proposed. The model is composed of spherical cells forming a hexagonal close-packed lattice. Tissue anisotropy is taken into account by varying interaction forces with the direction of intercellular connection.
Melnikova NB+3 more
europepmc +7 more sources
Scavenging of nitric oxide by hemoglobin in the tunica media of porcine coronary arteries. [PDF]
Scavenging of nitric oxide (NO) often interferes with studies on NO signaling in cell-free preparations. We observed that formation of cGMP by NO-stimulated purified soluble guanylate cyclase (sGC) was virtually abolished in the presence of cytosolic preparations of porcine coronary arteries, with the scavenging activity localized in the tunica media ...
Kollau A+8 more
europepmc +4 more sources
Immune cells and vasa vasorum in the tunica media of atherosclerotic coronary arteries. [PDF]
In coronary artery disease (CAD), the disruption of the tunica media immune privilege manifests as increased leukocyte infiltration and the formation of vasa vasorum. We aimed to characterize the immune privilege status of the tunica media in human coronary arteries (CAs) with atherosclerotic plaques, by comparing the abundance and composition of ...
Zorc-Pleskovič R+4 more
europepmc +4 more sources
Inflammatory cells in perivascular adipose tissue and the integrity of the tunica media in atherosclerotic coronary arteries. [PDF]
Obstructive coronary artery disease (CAD) is characterized by inflammation within the atherosclerotic coronary arteries. Infiltration of inflammatory cells into muscular media can lead to remodeling and weakening of the arterial wall. We examined the relationship between inflammatory infiltration in perivascular adipose tissue (PVAT), state of the ...
Zorc-Pleskovič R+3 more
europepmc +6 more sources
Structural Features in Tunica Media of the Aorta in Lamb [PDF]
In blood vessels situated just after the heart, an irregular blood flow occurs due to some specific structural elements of the tunica media. The current paper describes the histological aspects of some post-cardiac arterial sections in lamb.
CSIBI, Dalma+3 more
core +7 more sources
Non muscle cells in the tunica media of the aorta [PDF]
Knowledge of cellular composition of aortic tunica media is important to improve understanding of aortic pathology. The aorta of 6 healthy male goats was studied by electron microscopy to elucidate cell types within the tunica media. Glutaraldehyde fixed
Mwachaka, Philip M+2 more
core +4 more sources
Overexpression of Hyaluronan in the Tunica Media Promotes the Development of Atherosclerosis [PDF]
The arterial content of hyaluronan (HA) undergoes diffuse changes as part of the diabetic macroangiopathy. Because HA influences the phenotype of vascular cells in vitro such as proliferation, migration, and secretion, it is tempting to speculate that diabetes-induced hastened cardiovascular disease may be linked to the increased amount of HA.
Chai, Song+8 more
openaire +4 more sources