Results 161 to 170 of about 2,703,430 (294)

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt‐Dependent NAD+ De Novo Synthesis in Mice

open access: yesAging Cell, EarlyView.
In Qprt‐deficient mice, testicular NAD+ levels decline accelerated with age, leading to mitochondrial dysfunction, disrupted DSB repair, impaired meiotic sex chromosome inactivation, and germ cell loss. Nicotinamide riboside (NR) supplementation restores NAD+ levels and alleviates these defects, highlighting the importance of NAD+ de novo synthesis in ...
Yining Xu   +9 more
wiley   +1 more source

Konjac glucomannan defends against high-fat diet-induced atherosclerosis in rabbits by promoting the PI3K/Akt pathway

open access: yesHeliyon, 2023
Atherosclerosis (AS) is the main cause of cardiovascular disease and cerebral infarction, which seriously endanger human health. This study aimed to investigate konjac glucomannan (KGM) defends against high-fat diet-induced AS in rabbits by promoting the
Junting Weng   +5 more
doaj  

Gambaran Histologik Aorta Kelinci Yang Diinduksi Dengan Lemak Babi Dan Diberi Ekstrak Beras Hitam [PDF]

open access: yes, 2016
: Dyslipidemia is an abnormal lipid metabolism, marked by the alteration of lipid fractions within the blood plasma. World Health Organization reported that dyslipidemia was associated with heart diseases in general with 4 million deaths each year ...
Polii, L. S. (Lendy)   +2 more
core  

Late Life Supplementation of 25‐Hydroxycholesterol Reduces Aortic Stiffness and Cellular Senescence in Mice

open access: yesAging Cell, EarlyView.
25‐hydroxycholesterol (25HC) targets senescent cell anti‐apoptotic pathways (SCAPs) to reduce vascular cell senescence, favorably remodel aortic wall components, and reduce aortic stiffening with advancing age. ABSTRACT Stiffening of the aorta is a key antecedent to cardiovascular diseases (CVD) with aging.
Sophia A. Mahoney   +8 more
wiley   +1 more source

Deep Cross-media Knowledge Transfer [PDF]

open access: yesarXiv, 2018
Cross-media retrieval is a research hotspot in multimedia area, which aims to perform retrieval across different media types such as image and text. The performance of existing methods usually relies on labeled data for model training. However, cross-media data is very labor consuming to collect and label, so how to transfer valuable knowledge in ...
arxiv  

The Women of the Air Transport Auxiliary in Second World War Newsreels

open access: yesAustralian Journal of Politics &History, EarlyView.
A small, but revealing, set of Second World War newsreels exist that feature the pilots of the Air Transport Auxiliary (ATA). Newsreels are an important source of knowledge about the ideology of authorities in wartime Britain. The immense popularity of the cinema meant that newsreels became an important way for the government to communicate with the ...
Lisa J Hackett
wiley   +1 more source

Unusual Muscle-related Morphological Features Detected in the Cranial Cava Vein in 10-day-old Broiler Chickens

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine
The birds, in contrast to mammals, have two cranial cava veins. The two cranial cava veins and caudal cava vein are the largest veins in chickens. In general, veins have a wall consisting of 3 tunics: intima, media, and adventitia.
Vasile RUS   +2 more
doaj   +1 more source

Specific propagation directions for media of rhombic symmetry [PDF]

open access: yesarXiv, 2004
We reanalyze the problem of existence of longitudinal normals inside symmetry planes of piezoelectric crystals belonging to the symmetry class mm2. The equations determining components of longitudinal normals situated outside symmetry planes for media of this symmetry are discussed.
arxiv  

Quantification of multi-lumen blood vessel pathology in chronic traumatic encephalopathy [PDF]

open access: yes, 2017
BACKGROUND: Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disorder that had been largely ignored for decades since its initial characterization in 1928 by Dr. H. Martland. Within the last several years, a dramatic increase of attention in
Dell'Aquila, Kevin
core  

Dexamethasone is a regulator of clock genes in testicular peritubular cells

open access: yesAndrology, EarlyView.
Abstract Background We recently found that peritubular cells of the human testis are a dominant site of expression of the glucocorticoid receptor (GR; encoded by NR3C1). Activation of GR by dexamethasone (Dex) strongly influences the phenotype of cultured human testicular peritubular cells (HTPCs), causing massive changes of their proteome and ...
Harald Welter   +11 more
wiley   +1 more source

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