Results 31 to 40 of about 355,650 (306)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Tunneling spectroscopy of magnetic tunnel junctions [PDF]

, 2010
Drewello V. Tunneling spectroscopy of magnetic tunnel junctions. Bielefeld (Germany): Bielefeld University; 2010.In this thesis, magnetic tunnel junctions based on MgO barriers have been prepared and investigated.
Drewello, Volker
core  

Study on Lining Cracking Damage Mechanism and Control Optimization of Mudstone Railway Tunnel

Advances in Civil Engineering
Ensuring the long-term stability of tunnels in soft rock masses, particularly water-sensitive mudstone, poses a significant challenge in railway engineering.
Haoyang Zhu, Yanbin Luo, Wurong Jia, Jiangsheng Xie, Pingan Wang, Qingsong Wang, Shangkun Guo, Xianlin He, Malongzhi Wan   +8 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Perpendicular anisotropy in magnetic tunnel junctions [PDF]

, 2012
Kugler Z. Perpendicular anisotropy in magnetic tunnel junctions.
Kugler, Zoe
core  

McVey tunnel

, 2022
Scale approximately 1:12,000. 1000 feet to one inch. Vertical scale approximately 1:4,800. 400 feet to 1 inch.Color."Cross section of mountain 'A' to 'B' on line of McVey Tunnel.

core  

Return-to-Work and Early Functional Recovery Following Office-Based Ultrasound-Guided Microinvasive Carpal Tunnel Release: A Prospective Cohort Study

Medicina
Background and Objectives: Carpal tunnel release (CTR) has evolved toward increasingly less invasive techniques, with the aim of reducing procedural trauma and accelerating recovery.
Christian A. Lobos, Kyle Wilcox, Aidan Cottrell, Thomaz De Campos Silva, Shea Wilcox   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Coal and Gas Outburst Behavior in Gas-Bearing Tunnels Revealed Through an Interpretable ISSA-DNN Learning Framework

Geofluids
Coal and gas outbursts represent one of the most severe safety hazards during the construction of gas-bearing tunnels. Accurate risk prediction remains difficult because of complex geological conditions, limited sample sizes, and the inherent ...
Fangyin Wu, Wenbo Yang, Zhiyu Chen, Jian Yan, Wenyu Xu, Lina Wen   +5 more
doaj   +1 more source