Results 61 to 70 of about 2,776 (202)
Molecular evolution of the neurohypophysial hormone precursors in mammals: comparative genomics reveals novel mammalian oxytocin and vasopressin analogues [PDF]
Among vertebrates the neurohypophysial hormones show considerable variation. However, in eutherian mammals they have been considered rather conserved, with arginine vasopressin (AVP) and oxytocin (OT) in all species except pig and some relatives, where ...
Wallis, Michael
core +1 more source
Disparity of turbinal bones in placental mammals
Abstract Turbinals are key bony elements of the mammalian nasal cavity, involved in heat and moisture conservation as well as olfaction. While turbinals are well known in some groups, their diversity is poorly understood at the scale of placental mammals, which span 21 orders.
Quentin Martinez +11 more
wiley +1 more source
We investigated the adaptive genetic diversity within a population of Rhinopithecus bieti using amplicon sequencing. From 47 individuals, we identified 16 MHC class I sequences, revealing a low level of adaptive genetic variation. Although evidence for balancing selection, including positive selection and trans‐species polymorphism, was observed, these
Fei Long +8 more
wiley +1 more source
Hominids adapted to metabolize ethanol long before human-directed fermentation [PDF]
Paleogenetics is an emerging field that resurrects ancestral proteins from now-extinct organisms to test, in the laboratory, models of protein function based on natural history and Darwinian evolution. Here, we resurrect digestive alcohol dehydrogenases (
Benner, Steven A. +6 more
core +1 more source
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang +19 more
wiley +1 more source
Property of hepatitis B virus replication in Tupaia belangeri hepatocytes
The northern treeshrew (Tupaia belangeri) has been reported to be an effective candidate for animal infection model with hepatitis B virus (HBV). The objective of our study was to analyze the growth characteristics of HBV in tupaia hepatocytes and the host response to HBV infection.
Sanada, Takahiro +8 more
openaire +2 more sources
ABSTRACT The nasal cavity of European hedgehogs (Erinaceus europaeus) harbours a well‐developed olfactory system, essential for food provision and communication. Additionally, it acts as a first line of defence by preventing pathogens and irritants from reaching the lungs, thereby playing an important physiological role.
Yannick Van de Weyer +5 more
wiley +1 more source
Basal physiological parameters in domesticated tree shrews ( Tupaia belangeri chinensis ) [PDF]
Establishing non-human primate models of human diseases is an efficient way to narrow the large gap between basic studies and translational medicine. Multifold advantages such as simplicity of breeding, low cost of feeding and facility of operating make the tree shrew an ideal non-human primate model proxy.
WANG, Jing +10 more
openaire +2 more sources
Yunnan Province, the most serious scrub typhus endemic areas in China, provides abundant ecological resources that sustain parasite and host populations. The distribution of vector‐borne diseases is driven by interactions between hosts, vectors and the environment, revealing critical ecological dynamics.
Yun‐Yan Luo +8 more
wiley +1 more source
Hepatitis C virus infection of primary tupaia hepatocytes leads to selection of quasispecies variants, induction of interferon-stimulated genes and NF-kappaB nuclear translocation [PDF]
Systems for in vitro culture of Hepatitis C virus (HCV) are essential tools to analyse virus-cell interactions and to investigate relevant pathophysiological aspects of HCV infection.
Aldabe, R. (Rafael) +7 more
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