Results 131 to 140 of about 3,817,942 (325)

Therapeutic targeting of bleomycin‐induced pulmonary fibrosis by human bone marrow mesenchymal stem cell‐derived extracellular vesicles and/or pirfenidone: Impact of sex in mature adult mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell‐derived extracellular vesicles (BM‐MSC‐EVs) with an IPF treatment, pirfenidone (PFD), in mature adult mice with established pulmonary ...
Jennie S. Charoenphannathon   +4 more
wiley   +1 more source

On the Design of Turbo Codes.

open access: yes, 2000
This thesis is about Turbo codes - codes constructed via parallel concatenation of two recursive convolutional encoders linked by an interleaver. The focus of the work is on the understanding and design of Turbo codes. This includes thorough investigation of central components that influence Turbo code performances, such as the constituent encoders and
openaire   +1 more source

Space-Time Codes and Concatenated Channel Codes for Wireless Communications [PDF]

open access: yes, 2002
Following a brief historical perspective on channel coding, an introduction to space–time block codes is given. The various space–time codes considered are then concatenated with a range of channel codecs, such as convolutional and block-based turbo ...
Liew, T.H., Hanzo, Lajos
core  

Inducible tomato defences persist in detached leaves, despite differential plant variety and gene‐dependent expression

open access: yesEcological Entomology, EarlyView.
Short‐ and long‐term expression of PPO‐D, PI‐IIc and PR‐1a were assessed in intact plants and detached tomato leaves of two varieties infested with Tetranhycus urticae. Tomato defences were induced in both intact and detached leaves, but the induction levels varied with plant variety and gene assessed.
Mariya Kozak   +6 more
wiley   +1 more source

RNF13 is a previously undescribed interactor of iduronate 2‐sulfatase that modifies its glycosylation and maturation

open access: yesThe FEBS Journal, EarlyView.
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana   +4 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

open access: yesThe FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo   +4 more
wiley   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

open access: yesThe FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo   +6 more
wiley   +1 more source

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

open access: yesThe FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal   +4 more
wiley   +1 more source

Space-Time Trellis and Space-Time Block Coding Versus Adaptive Modulation and Coding Aided OFDM for Wideband Channels [PDF]

open access: yes, 2006
—The achievable performance of channel coded spacetime trellis (STT) codes and space-time block (STB) codes transmitted over wideband channels is studied in the context of schemes having an effective throughput of 2 bits/symbol (BPS) and 3 BPS.
Liew, T.H., Hanzo, L.
core  

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer   +4 more
wiley   +1 more source

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