Results 141 to 150 of about 1,593,061 (277)

microRNA‐145‐5p regulates P‐glycoprotein and breast cancer resistance protein in primary human fetal brain endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Drug transporters P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) at the blood–brain barrier (BBB) protect the rapidly developing fetal brain. We investigated the role of microRNA‐145‐5p (miR‐145‐5p) microRNA (miRNA) in regulating these key transporters in primary human fetal brain endothelial cells in vitro. We
Phetcharawan Lye   +5 more
wiley   +1 more source

Inter-Shot Motion Correction of Segmented 3D-GRASE ASL Perfusion Imaging With Self-Navigation and CAIPI. [PDF]

open access: yesMagn Reson Med
ABSTRACT Purpose Segmented 3D Gradient and Spin Echo (GRASE) is commonly used in Arterial Spin Labeling (ASL) perfusion imaging. However, it is vulnerable to inter‐shot motion, leading to subtraction errors that cannot be corrected. We developed a retrospective self‐navigated inter‐shot motion correction method for segmented 3D‐GRASE ASL imaging with ...
Hu M   +5 more
europepmc   +2 more sources

PRECISE: Reducing the bias of LLM evaluations using prediction‐powered ranking estimation

open access: yesAI Magazine, Volume 47, Issue 4, Winter 2026.
Abstract Evaluating the quality of search systems traditionally requires a significant number of human relevance annotations. In recent times, several systems have explored the usage of Large Language Models (LLMs) as automated judges for this task while their inherent biases prevent direct use for metric estimation.
Abhishek Divekar, Anirban Majumder
wiley   +1 more source

Multimodal foundation models exploit text to make medical image predictions. [PDF]

open access: yesNat Commun
Buckley TA   +6 more
europepmc   +1 more source

p‐Brain: A Modular Open‐Source Framework for Automated Quantitative DCE‐MRI of Cerebral Perfusion, Microvasculature, and Blood–Brain Barrier Permeability

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 6, Page 2601-2614, December 2026.
ABSTRACT We present p‐Brain, a modular, open‐source framework for reproducible, automated quantitative DCE‐MRI at scale. Rather than a fixed pipeline, p‐Brain is built from interchangeable stages (ingestion, T1/M0$$ {T}_1/{M}_0 $$ fitting, vascular and tissue ROI extraction, signal‐to‐concentration conversion, kinetic modeling, and quality control ...
Edis D. Tireli   +5 more
wiley   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

open access: yesGlia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson   +13 more
wiley   +1 more source

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