Results 141 to 150 of about 148,871 (301)
Fast Correlation Attacks Based on Turbo Code Techniques
, 1999 Thomas Johansson, Fredrik Jönsson
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On the theory and performance of trellis termination methods for turbo codes [PDF]
, 2001 Johan Hokfelt +2 more
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The FEBS Journal, EarlyView.Here, we explore a differential sex‐related metabolic‐immune relationship in melanoma. Melanoma tumours in male patients exhibit a higher LDH‐A‐driven production of lactate compared to their female counterparts. In turn, lactate acts as an immunosuppressive molecule, promoting pro‐tumoural Treg cells and suppressing anti‐tumoural CD8+ T‐cell activity ...
Marta Iozzo +10 more
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Turbo-coded parallel modem techniques for personal communications [PDF]
, 2002 Thomas Keller +2 more
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Functional consequences of lysine acetylation of phosphofructokinase isozymes
The FEBS Journal, EarlyView.Here, we investigated the impact of lysine acetylation on phosphofructokinase (Pfk) isozyme activity using a genetic code expansion strategy. We found that the acetylation of lysine residues in Pfk isozymes in Escherichia coli affects the activities of these enzymes and is generated by non‐enzymatic acetylation with acetyl phosphate.
Xinyu Li +3 more
wiley +1 more source
Hydromethylthionine sustains truncated tau‐dependent inflammation‐lowering effects in mouse brain
The FEBS Journal, EarlyView.Hydromethylthionine (HMT) is an inhibitor of tau protein aggregation, but one that appears to be affected in subjects already receiving symptomatic treatments for dementia, such as memantine. We found that HMT decreased both tau aggregation and neuroinflammation in transgenic mice in a manner that was unaffected by memantine.
Renato X. Santos +13 more
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The FEBS Journal, EarlyView.N6‐methyladenosine is a key mRNA modification that regulates transcript turnover, translation, and other aspects of RNA fate. The m6A‐demethylase ‘eraser’ enzyme FTO reverses this modification. While FTO is known to promote oncogenic signaling in triple‐negative breast cancer, its wider role across the genome and specific downstream signaling has yet ...
Hidde R. Zuidhof +6 more
wiley +1 more source
Derivatives of MOPS: promising scaffolds for SARS coronaviruses Macro domain‐targeted inhibition
The FEBS Journal, EarlyView.The SARS‐CoV/CoV‐2 genome encodes non‐structural protein 3, which contains a ‘Macro domain’. This protein domain exhibits antagonistic activity against interferon signaling, which disrupts the host innate immune response and can thus mediate viral escape, highlighting its therapeutic potential.
Oney Ortega Granda +5 more
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The FEBS Journal, EarlyView.We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika +7 more
wiley +1 more source
The FEBS Journal, EarlyView.In healthy neurons, Protein kinase A (PKA) forms a tetrameric holoenzyme enabling precise allosteric regulation. We characterized a novel neurodegenerative disease, neuronal loss, and parkinsonism driven by PRKAR1B mutation (NLPD‐PKA), demonstrating disrupted holoenzyme assembly, reduced cooperativity, and increased catalytic subunit nuclear ...
Tal Benjamin‐Zukerman +13 more
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