Results 171 to 180 of about 6,362 (245)

Effects of Physical Activity on Brain White Matter Integrity Are Region‐, Dose‐, and Age‐Dependent: Findings From the Population‐Based Rhineland Study

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Physical activity is related to more aligned white matter fibers and microstructural reorganization of the brain. Body weight, cardiometabolic, and inflammatory factors could partly mediate the effects of physical activity on brain white matter microstructure. The effects of physical activity on the brain are age‐ and region‐specific.
Eva Saxler   +7 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4399-4415, August 2026.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci   +15 more
wiley   +1 more source

AlquistCoder: A Synthetic Data Approach to Training Compact Secure Coding Assistants and Building Security Benchmarks

open access: yesComputational Intelligence, Volume 42, Issue 4, August 2026.
ABSTRACT Large language models are increasingly used as programming assistants, but their security behavior remains uneven: they may generate code with vulnerable patterns, and they may provide actionable help for malicious requests. This paper introduces AlquistCoder, a compact 3.8B‐parameter coding assistant designed to address both risks through ...
Ondřej Kobza   +6 more
wiley   +1 more source

Small Language Models: A Systematic Review of Computational Trade‐Offs, Privacy Advantages and Deployment in Intelligent Systems

open access: yesExpert Systems, Volume 43, Issue 8, August 2026.
ABSTRACT This systematic review synthesizes evidence from 68 studies, including peer‐reviewed journal articles, indexed conference/workshop proceedings and five remaining arXiv preprints published between 2022 and 2025, on small language models (SLMs) as computationally efficient alternatives to large language models (LLMs).
Sena Dikici, Turgay Tugay Bilgin
wiley   +1 more source

Extracting TNFi switching reasons and trajectories from real-world data using large language models. [PDF]

open access: yesJAMIA Open
Miao BY   +10 more
europepmc   +1 more source

Detecting Opioid Misuse on Social Media via Named Entity Recognition (NER) With Deep Learning

open access: yesExpert Systems, Volume 43, Issue 8, August 2026.
ABSTRACT The opioid overdose epidemic constitutes a critical public health crisis, necessitating advanced surveillance tools to enable timely intervention. Social media platforms provide a real‐time source of information on drug‐related behaviours. However, extracting structured knowledge from their informal, slang‐heavy and fragmented text presents ...
Muhammad Ahmad   +4 more
wiley   +1 more source

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