Results 61 to 70 of about 464 (157)

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

EE2 and the Fish Brain: Age‐Dependent Impact of 17α‐Ethinylestradiol on Brain Cell Proliferation and Behavior in Sea Bass Larvae

Environmental Toxicology, EarlyView.
ABSTRACT Endocrine‐disrupting chemicals (EDCs), such as 17α‐ethinylestradiol (EE2), have raised concerns about their potential effects on aquatic organisms, particularly during early developmental stages. In this context, the study of behavioral disruption has gained considerable attention, as it may have consequences on individual fitness and ...
Soloperto Sofia, Stephanie Olivier, Céline Thomasse, Christophe Minier, Marie‐Pierre Halm‐Lemeille, Christelle Jozet‐Alves, Salima Aroua   +6 more
wiley   +1 more source

Bridging the Late Antique Gap in Northwest Arabia: New Archaeological Evidence on the Occupation of Wādī al‐Qurā (al‐ʿUlā [AlUla], Saudi Arabia) Between the Third and Seventh Centuries CE

Arabian Archaeology and Epigraphy, EarlyView.
ABSTRACT In 2019, the Dadan Archaeological Project (CNRS/RCU/AFALULA) identified a Late Antique village 1 km south of ancient Dadan in the al‐ʿUlā valley (northwest Saudi Arabia). Three excavation seasons at this site (2021–2023) have uncovered a massive building constructed in the late third or early fourth cent.
Jérôme Rohmer, Abdulrahman Alsuhaibani, Charlène Bouchaud, Elora Chambraud, Vladimir Dabrowski, Hatem Djerbi, Fabien Lesguer, Hervé Monchot, Paul Picavet, Louise Purdue, Bertrand Riba, Shadi Shabo   +11 more
wiley   +1 more source

Transformation of an ordinary ring road intersection into a turbo ring intersection: bandwidth comparison 

Интеллект. Инновации. Инвестиции, 2020
In large cities, a situation often arises when roundabout intersections of highways no longer cope with the passage of traffic flows. The main reasons for this problem are the inconsistency of the potential traffic capacity of the roundabout with real ...
V. I. Rassokha , N. A. Nikitin
doaj   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

International Journal of Cancer, Volume 159, Issue 1, Page 144-158, 1 July 2026.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho, Fabio Nunes de Mello, Ana Carolina Tahira, Gabriel Nakanishi Fortes, Agatha Fischer‐Carvalho, Pedro Jardim Poli, Murilo Sena Amaral, Sergio Verjovski‐Almeida   +7 more
wiley   +1 more source

A Shock‐Tube Study of the HCl + M →$\to $ H + Cl + M (M = Ar) Rate Constant Using HCl Laser Absorption Near 3.3 µm

International Journal of Chemical Kinetics, Volume 58, Issue 7, Page 371-382, July 2026.
ABSTRACT Hydrogen chlorine (HCl) is an important combustion intermediate during plastic (municipal waste) and composite propellant (aerospace) combustion, but the understanding of its high‐temperature chemistry is still evolving. In this study, the pyrolysis of 0.5% HCl in Ar was investigated behind reflected shock waves in a shock tube at temperatures
Claire M. Grégoire, Olivier Mathieu, Eric L. Petersen   +2 more
wiley   +1 more source

Hierarchically Porous Coatings for Cellulose Fibers by Core–Shell Particle Templating

Macromolecular Rapid Communications, Volume 47, Issue 13, 3 July 2026.
Hybrid and functional core–shell particles comprising a silica core and a polymer shell were synthesized and used to develop a coating and etching process applied to a cellulose substrate. This resulted in highly porous, functional coatings on a cellulose membrane for further application in cellulose‐based adsorbers and advanced membrane technology ...
Regina Leiner, Derya Kurt, Sebastian Heinz, Volker Presser, Bizan N. Balzer, Markus Gallei   +5 more
wiley   +1 more source

Evaluation of Roundabout Safety Performance through Surrogate Safety Measures from Microsimulation

Journal of Advanced Transportation, 2018
The paper presents a microsimulation-based approach for roundabout safety performance evaluation. Based on a sample of Slovenian roundabouts, the vehicle trajectories exported from AIMSUN and VISSIM were used to estimate traffic conflicts using the ...
Orazio Giuffrè, Anna Granà, Maria Luisa Tumminello, Tullio Giuffrè, Salvatore Trubia, Antonino Sferlazza, Marko Rencelj   +6 more
doaj   +1 more source

USING A MICROSIMULATION TRAFFIC MODEL TO COMPARE TWO-LANE AND TURBO-ROUNDABOUTS

, 2015
Microsimulation traffic models are used to analyze and predict the functionality and safety of traffic networks, especially in critical areas such as intersections.
Ivan Kolak, Irena Ištoka Otković, Ivana Barišić   +2 more
openalex   +3 more sources