Results 71 to 80 of about 1,545,629 (253)

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Turbulence transport throughout the heliosphere [PDF]

, 2007
We employ a turbulence transport model to compute distributions of turbulence throughout the heliosphere. The model determines the radial dependence of three (coupled) quantities that characterize interplanetary turbulence, the energy per unit mass, the ...
Matthaeus, William H., Oughton, Sean, Minnie, J., Smith, Charles W., Bieber, J.W., Isenberg, P.A., Breech, Ben   +6 more
core   +2 more sources

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

A Comparative Study of Pilot Reports and In Situ EDR Measurements of Aircraft Turbulence

Atmosphere
Accurate characterization of aircraft turbulence is vital for aviation safety and efficiency. This study leverages 2021 data from nationwide Pilot Reports (PIREPs) and China Eastern Airlines’ in situ Eddy Dissipation Rate (EDR) measurements to ...
Jingyuan Shao, Yi Li, Yan Yu Leung, Zhenyu Yu, Kaijun Wu, Wenhan Gu, Yiqin Bai, Pak-Wai Chan, Zibo Zhuang   +8 more
doaj   +1 more source

Direct numerical simulations of transition in a compressor cascade: The influence of free-stream turbulence [PDF]

, 2010
Copyright © Cambridge University Press 2010.The flow through a compressor passage without and with incoming free-stream grid turbulence is simulated.
TAMER A. ZAKI, Rodi, W, Durbin, PA, JAN G. WISSINK, WOLFGANG RODI, Wissink, JG, Zaki, TA, PAUL A. DURBIN   +7 more
core   +1 more source

A Compact Hollow Fiber Electrode Assembly Architecture for Continuous Electrochemical Marine Carbon Dioxide Removal

Advanced Energy Materials, EarlyView.
A coaxial, membrane‐integrated hollow fiber electrode assembly (HFEA) is developed for continuous marine carbon mineralization. By utilizing a sub‐millimeter inter‐electrode gap, the HFEA minimizes Ohmic losses, achieving 50% energy reduction and over 85% DIC removal.
Inhwan Park, Young Hun Lee, Jung Hun Lee, Seung‐Jeong Oh, T. Alan Hatton, Dong‐Yeun Koh   +5 more
wiley   +1 more source

Wind Turbulence Intensity at La Ventosa, Mexico: A Comparative Study with the IEC61400 Standards

Energies, 2018
Wind speed turbulence intensity is a crucial parameter in designing the structure of wind turbines. The IEC61400 considers the Normal Turbulence Model (NTM) as a reference for fatigue load calculations for small and large wind turbines.
C. A. Lopez-Villalobos, O. Rodriguez-Hernandez, R. Campos-Amezcua, Guillermo Hernandez-Cruz, O. A. Jaramillo, J. L. Mendoza   +5 more
doaj   +1 more source

Return and Volatility Spillovers Among Major Cotton Markets

Agribusiness, EarlyView.
ABSTRACT This study explores return and volatility transmission among major cotton markets. Several events have disrupted cotton supply and demand in recent years, leading to heightened price volatility and significant shifts in market interconnections.
Susmitha Kalli, Berna Karali, Yangxuan Liu, Munisamy Gopinath   +3 more
wiley   +1 more source

Modeling of the Effects of Turbulence Intensity on Mechanical Hemolysis of Red Blood Cells

مجله دانشکده پزشکی اصفهان, 2012
Background: Mechanical hemolysis plays an important role in development of cardiovascular prostheses, artificial valves, and blood pumps. Considerable research has been conducted to investigate mechanical hemolysis of red blood cells (RBC). Most previous
Amir Omidvar, Hassan Khaleghi, Elham Amini   +2 more
doaj  

Mapping the Innovation DNA of Agribusiness Firms: A Multi‐Method Analysis of Strategic Capabilities and Performance

Agribusiness, EarlyView.
ABSTRACT Innovation is essential for competitiveness in agribusiness facing dynamic environments. This study examines how market orientation, marketing, relational, and social capabilities influence innovation performance. Using data from 751 Spanish firms and a multi‐method approach that integrates Structural Equation Modeling (PLS‐SEM), Necessary ...
Beatriz Corchuelo Martínez‐Azúa, Alvaro Dias   +1 more
wiley   +1 more source