Results 151 to 160 of about 3,253,485 (285)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Experiments on flow over obstacle arrays: a database for turbulent flow and wave transformation modeling. [PDF]

Sci Data
Cantero-Chinchilla FN, Castro-Orgaz O, Ali SZ, Dey S.   +3 more
europepmc   +1 more source

Distribution and history of extensional stresses on vWF surrogate molecules in turbulent flow. [PDF]

Sci Rep, 2022
Pham OL, Feher SE, Nguyen QT, Papavassiliou DV.   +3 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Wind tunnel measurement dataset of turbulent flow over two-dimensional ridges and three-dimensional hills with smooth and rough surfaces. [PDF]

Data Brief
Ishihara T, Zhou T.
europepmc   +1 more source

Effect of crucible wall roughness on the laminar/turbulent flow transition of the Ga75In25 alloy stirred by a rotating magnetic field. [PDF]

Sci Rep, 2022
Roósz A, Rónaföldi A, Svéda M, Veres Z.   +3 more
europepmc   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Strong turbulent flow in the subauroral region in the Antarctic can deteriorate satellite-based navigation signals. [PDF]

Sci Rep
Kotova DS, Sinevich AA, Chernyshov AA, Chugunin DV, Jin Y, Miloch WJ.   +5 more
europepmc   +2 more sources

Acceleration is the key to drag reduction in turbulent flow. [PDF]

Proc Natl Acad Sci U S A
Ding L, Sabidussi LF, Holloway BC, Hultmark M, Smits AJ.   +4 more
europepmc   +1 more source

Characterization of Turbulent Flow Behind a Transcatheter Aortic Valve in Different Implantation Positions. [PDF]

Front Cardiovasc Med, 2021
Pietrasanta L, Zheng S, De Marinis D, Hasler D, Obrist D.   +4 more
europepmc   +1 more source