Results 141 to 150 of about 122,095 (310)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

TURBULENCE OF BLOOD FLOW [PDF]

Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1959
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

On the significance of form induced stress in rough wall turbulent boundary layers

, 2008
This paper presents a review of recent experimental and numerical studies which deal with the analysis of form-induced stress in rough wall turbulent boundary layers.
Costantino Manes, Manes, Constatino, Pokrajac, D., Manes, Costantino, Coceal, Omduth, McEwan, I.K., Pokrajac, Dubravka, Omduth Coceal, Dubravka Pokrajac, Manes, C., POKRAJAC D, COCEAL O, MCEWAN IK, Coceal, O., McEwan, Ian, Mcewan, Ik, Ian McEwan   +16 more
core   +1 more source

Investigation of Particles Statistics in large Eddy Simulated Turbulent Channel Flow using Generalized lattice Boltzmann Method

Journal of Applied Fluid Mechanics, 2016
The interaction of spherical solid particles with turbulent eddies in a 3-D turbulent channel flow with friction Reynolds number was studied. A generalized lattice Boltzmann equation (GLBE) was used for computation of instantaneous turbulent flow field
Mandana Samari Kermani, Saeed Jafari, Mazyar Salmanzadeh, Mohamad Rahnama   +3 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

RANS Computation of Low Speed Turbulent Flow in Complex Configuration [PDF]

An implicit finite volume algorithm based on the numerical solution of Reynolds Averaged Navier stokes (RANS) equation is presented for prediction of incompressible turbulent flow in and around complex configuration.
Mohan, Sripathi, Majumdar, Sekhar, Kulkarni, DS, Rajani, BN   +3 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Investigation of high-resolution methods in large-eddy simulation of subsonic and supersonic wall turbulent flows

, 2009
This thesis presents the motivation, objectives and reasoning behind the undertaken PhD to investigate the capability of compressible Implicit Large Eddy Simulation (ILES) in simulating wall-bounded inhomogeneous flows with particular interest in the ...
Kokkinakis, Ioannis William
core  

Topology Optimization of Turbulent Flow Cooling Structures Based on the k-ε Model. [PDF]

Entropy (Basel), 2023
Sun Y, Hao M, Wang Z.
europepmc   +1 more source