Results 121 to 130 of about 122,095 (310)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Direct numerical simulation of turbulent flow past a trailing edge and the associated noise generation

, 2008
Direct numerical simulations (DNS) are conducted of turbulent flow passing an infinitely thin trailing edge (TE). The objective is to investigate the turbulent flow field in the vicinity of the TE and the associated broadband noise generation.
Sandberg, Richard D., Sandham, Neil D.
core   +1 more source

Changing of energy dissipation in the transition of laminar flow to turbulence (rus) [PDF]

Инженерно-строительный журнал, 2011
Under the same fixed dynamical boundary conditions the energy dissipation in laminar and turbulent flow are compared. As examples the flow past a plate and the flow through a pipe are considered.
Girgidov A.D.
doaj  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

An investigation into the structure of a turbulent plane jet.

, 1963
PhDAn experimental investigation into the structure of the plane jet in a moving airstream has been made. The majority of the measurements have been made in a jet exhausting into a slow moving airstream providing an example of a possible self ...
Bradbury, L. J. S
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Large-eddy simulation of low-frequency unsteadiness in a turbulent shock-induced separation bubble

, 2009
The need for better understanding of the low-frequency unsteadiness observed in shock wave/turbulent boundary layer interactions has been driving research in this area for several decades.
Touber, Emile, Sandham, Neil D.
core   +1 more source

Turbulence Modeling of Torsional Couette Flows

International Journal of Rotating Machinery, 2008
The present study considers the numerical modeling of the turbulent flow inside a rotor-stator cavity subjected or not to a superimposed throughflow.
Sofia Haddadi, Sébastien Poncet
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Characteristics of turbulence in free convection flow past a vertical plate.

, 1972
PhDAn experimental and theoretical investigation of the turbulent free convection boundary layer on a vertical plane surface in air has been conducted.
Smith, Ronald Robin
core