Results 41 to 50 of about 122,095 (310)

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Numerical simulations of drag modulation by microbubbles in a turbulent Taylor-Couette flow [PDF]

, 2013
The aim of our study is to investigate numerically the interaction between a dispersed phase composed of microbubbles and a turbulent Taylor-Couette flow (flow within the gap between two cylinders).
CLIMENT, Eric, GABILLET, Céline, LEGENDRE, Dominique, CHOUIPPE, Agathe   +3 more
core  

Structure of turbulent flow over regular arrays of cubical roughness. [PDF]

, 2007
The structure of turbulent flow over large roughness consisting of regular arrays of cubical obstacles is investigated numerically under constant pressure gradient conditions.
Thomas, T.G., Dobre, A., Coceal, O., Thomas, T. G., Belcher, S.E., Belcher, S. E.   +5 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Numerical investigation of turbulent flow heat transfer and pressure drop of AL2O3/water nanofluid in helically coiled tubes [PDF]

, 2013
Passive convective heat transfer enhancement can be achieved by improving the thermo-physical properties of the working fluid, changing flow geometry or both.
Mahmoud, Saad, Al-dadah, Raya K., Al-dadah, Raya, Rezk, A., Rezk, Ahmed, Al-dadah, R. K., Elsayed, Ahmed, Mahmoud, S.   +7 more
core   +1 more source

Large-Scale Flow Structure in Turbulent Poiseuille Flows at Low-Reynolds Numbers

Journal of Fluid Science and Technology, 2012
Direct numerical simulations of a spectral method are performed to study the turbulent channel flow at the low-Reynolds numbers, where the quasi-laminar and turbulent regions simultaneously appear and form the stripe pattern, which is floated downstream ...
Koji FUKUDOME, Oaki IIDA
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Direct numerical simulation of a turbulent flow using a spectral/hp element method

, 2006
Direct numerical simulation (DNS) of incompressible turbulent pipe flow was carried out on unstructured grids for a Reynolds number based on the friction velocity and the pipe diameter of Re τ = 360 using the spectral/hp element method (SEM) by ...
Shishkin, Andrei, Claus Wagner, Andrei Shishkin, Wagner, Claus   +3 more
core   +1 more source