Results 51 to 60 of about 3,253,485 (285)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Numerical simulation of bubble dispersion in turbulent Taylor-Couette flow [PDF]

, 2014
We investigate bubble dispersion in turbulent Taylor-Couette flow. The aim of this study is to describe the main mechanisms yielding preferential bubble accumulation in near-wall structures of the flow.
CLIMENT, Eric, D. Legendre, GABILLET, Céline, E. Climent, C. Gabillet, LEGENDRE, Dominique, CHOUIPPE, Agathe, A. Chouippe   +7 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Scale-to-scale information flow amplifies turbulent fluctuations

Physical Review Research
In three-dimensional turbulence, information of turbulent fluctuations at large scales is propagated to small scales. Here, we investigate the relation between the information flow and turbulent fluctuations described by a shell model. We first establish
Tomohiro Tanogami, Ryo Araki
doaj   +1 more source

Large-eddy simulation of wall-bounded turbulent flow with high-order discrete unified gas-kinetic scheme

Advances in Aerodynamics, 2020
In this paper, we introduce the discrete Maxwellian equilibrium distribution function for incompressible flow and force term into the two-stage third-order Discrete Unified Gas-Kinetic Scheme (DUGKS) for simulating low-speed turbulent flows.
Rui Zhang, Chengwen Zhong, Sha Liu, Congshan Zhuo   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Numerical simulations of drag modulation by microbubbles in a turbulent Taylor-Couette flow [PDF]

, 2013
The aim of our study is to investigate numerically the interaction between a dispersed phase composed of microbubbles and a turbulent Taylor-Couette flow (flow within the gap between two cylinders).
CLIMENT, Eric, GABILLET, Céline, LEGENDRE, Dominique, CHOUIPPE, Agathe   +3 more
core  

Direct numerical simulation of a turbulent flow using a spectral/hp element method [PDF]

, 2006
Direct numerical simulation (DNS) of incompressible turbulent pipe flow was carried out on unstructured grids for a Reynolds number based on the friction velocity and the pipe diameter of Re τ = 360 using the spectral/hp element method (SEM) by ...
Shishkin, Andrei, Claus Wagner, Andrei Shishkin, Wagner, Claus   +3 more
core   +1 more source

timghill/subglacial-laminar-turbulent-flow: v1.0.0

, 2023
Supplementary code for "Improved representation of laminar and turbulent sheet flow in subglacial drainage models" (Hill et al ...
Tim Hill
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source