Results 121 to 130 of about 113,224 (304)

Three-layer circulation in the world deepest hadal trench

Nature Communications
The Challenger Deep (CD) is the deepest known hadal trench in the world. Due to challenges in data sampling at extreme ocean depths, the Lower Circumpolar Deep Water (LCDW) transport and ocean circulation structure in the CD remain unclear.
Huichang Jiang, Xiao Xin, Hongzhou Xu, Chun Zhou, Philip A. Vetter, Liu Yu, Tong Long, Qi’an Chen, Jiwei Tian   +8 more
doaj   +1 more source

Impact of Internal Solitary Waves on Marine Suspended Particulate Matter: A Review

Journal of Marine Science and Engineering
Suspended particulate matter (SPM) plays a pivotal role in marine source-to-sink sedimentary systems. Internal solitary waves (ISWs), a prevalent hydrodynamic phenomenon, significantly influence vertical mixing, cross-shelf material transport, and ...
Zhengrong Zhang, Xuezhi Feng, Xiuyao Fan, Yuchen Lin, Chaoqi Zhu   +4 more
doaj   +1 more source

Transport and mixing by finite-size particles in turbulent flows

, 2022
   Suspensions of solid particles in a viscous fluid are ubiquitous in natural and engineering settings, including sediment transport in river beds, blood flow in the human body, oil products transport in pipelines and pulp fibers in papermaking.     Multiphase flows consisting of finite-size particles is a challenging topic due to multi-way coupling ...
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Transport phenomena in chaotic flows: flux recombination HEX reactors [PDF]

, 2012
Rapid transport of heat and mass is required in many industrial processes. Mixing is a fundamental issue in chemical engineering applications and when exothermic reactions are involved, heat transfer capabilities of reactors and static mixers become an ...
A. Ghanem, D. Della Valle, H. Peerhossaini, T. Lemenand   +3 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Prediction of heat release effects on a mixing layer [PDF]

A fully second-order closure model for turbulent reacting flows is suggested based on Favre statistics. For diffusion flames the local thermodynamic state is related to single conserved scalar.
Farshchi, M.
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Turbulent transport and length scale measurement experiments with comfined coaxial jets [PDF]

A three phase experimental study of mixing downstream of swirling and nonswirling confined coaxial jets was conducted to obtain data for the evaluation and improvement of turbulent transport models currently employed in a variety of computational ...
Johnson, B. V., Roback, R.
core   +1 more source