Results 101 to 110 of about 113,224 (304)

Mass and momentum turbulent transport experiments with confined swirling coaxial jets [PDF]

Swirling coaxial jets mixing downstream, discharging into an expanded duct was conducted to obtain data for the evaluation and improvement of turbulent transport models currently used in a variety of computational procedures throughout the combustion ...
Johnson, B. V., Roback, R.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Vertical transport in the atmosphere: Measurement capabilities and requirements of VHF radars, part 1.6A [PDF]

Mass exchange, mixing on transport in the atmosphere involves reversible processes, i.e., any kind of organized motions such as wave and large scale flows, and nonreversible processes, i.e., molecular and turbulent diffusion. Without evaluating in detail
Rottger, J.
core   +1 more source

Numerical experiments on scalar transport and mixing in turbulent boundary layers

Journal of Physics: Conference Series
Abstract In this work, we present numerical experiments aimed at dynamically establishing the separate role of the inner and outer cycles on the scalar transport in the configuration of a temporally evolving boundary layer. The experiments are based on the study of the evolution of passive scalars driven by velocity fields where inner ...
Boga G., Giancola A., Cimarelli A.
openaire   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Multi‐Scale Physical Modulation of Surface‐Layer Wind Profile and Momentum Flux in the Peripheral Circulation of Super Typhoon Yagi

Geophysical Research Letters
This study presents analysis of the nearshore marine atmospheric surface layer during Super Typhoon Yagi using detailed observational data. As the typhoon's peripheral circulation intensified, wind speeds increased across the observed heights (16.4–35.1 ...
Jing Liang, Lei Li, Pak Wai Chan, Qianjin Zhou, Ling Huang, Sheng Hu   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Second-order closure models for supersonic turbulent flows [PDF]

Recent work on the development of a second-order closure model for high-speed compressible flows is reviewed. This turbulent closure is based on the solution of modeled transport equations for the Favre-averaged Reynolds stress tensor and the solenoidal ...
Sarkar, Sutanu, Speziale, Charles G.
core   +1 more source

The influence of large-scale motion on turbulent transport for confined coaxial jets [PDF]

, 1984
The existence of large-scale coherent structures in turbulent shear flows has been well documented in the literature. The importance of these structures in flow entrainment, momentum transport and mass transport in the shear layer has been suggested by ...
Bennett, J. C., Brondum, D. C.
core   +1 more source